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Gene Therapy for Neurological Disorders and Brain Tumors E. Antonio Chiocca

Gene Therapy for Neurological Disorders and Brain Tumors By E. Antonio Chiocca

Gene Therapy for Neurological Disorders and Brain Tumors by E. Antonio Chiocca


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Summary

Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology.

Gene Therapy for Neurological Disorders and Brain Tumors Summary

Gene Therapy for Neurological Disorders and Brain Tumors by E. Antonio Chiocca

Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology. The authoritative contributors provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potential strategies against neurologic disorder, and the limitations of today's gene therapy approaches. Also discussed are significant applications of gene therapy to brain tumors, Parkinson's disease, ischemia, and Huntington's chorea. Readers will learn the current delivery methods for transgenes, will learn the characteristics of transgene delivery vectors, and come to understand the therapy for both neuro-oncologic and neurologic disorders.

Gene Therapy for Neurological Disorders and Brain Tumors Reviews

a very interesting book. . .all 'gene therapy laboratories' and 'neuo-gene therapy laboratories' will be able to derive much intellectual nourishment and stimulation, practical tips, and predictions about the future from this truly challenging volume.-Human Genetics

Table of Contents

Part i: Vectors and Promoters. Introduction, J. Glorioso. Retrovirus Vectors and Regulatable Promoters, S. Reeves. Adenovirus Vectors, M. Cotten. Herpes Simplex Virus: Recombinant Vectors, P. A. Johnson. Herpes Simplex Virus: Amplicon Vectors, C. Fraefel, X. O. Breakefield, and D. Jacoby. Adeno-Associated Virus Vectors, F. I. Smith and T. J. McCown. Epstein-Barr Virus Vectors, J.-M. H. Vos, K. B. Quattrocchi, and B. J. Wendelburg. Lentiviral Vectors, D. Trono, U. Blomer, and L. Naldini. Promoters for Expression of Gene Products Within Neurons and Glia, J. W. Henson. Immunological Issues, J. G. Smith and S. L. Eck. Part ii: Neuro-oncology. Current Treatment Modalities for Brain Tumor, S. B. Tatter and G. R. Harsh IV. Experimental and Clinical Gene Therapies for Brain Tumors, E. A. Chiocca. Tumor Suppressor Gene Therapy for Brain Tumors, C. Gomez-Manzano, J. Fueyo, A. P. Kyritsis, W.K. A. Yung. Cytokine-Based Gene Therapy for Brain Tumors, J. H. Sampson, D. D. Bigner, and G. Dranoff. Delivery of Therapeutic Genes to Brain and Intracerebral Tumors, L. L. Muldoon, R. A. Kroll, M. A. Pagel, S. Roman-Goldstein, and E. A. Neuwelt. Rat Brain Tumor Models and Statistical Evaluation of Survival Data in Experimental Neuro-Oncology, R. F. Barth and M. L. Moeschberger. Part iii: Neurological Disorders. Neurological Disorders: An Overview, A. B. Young. Gene Transfer for Adult CNS Regeneration and Aging, M.C. Senut, I. Aubert, P.J. Horner, and F. H. Gage. Gene Therapy for Parkinson's Disease, M. C. Bohn and D. L. Choi-Lundberg. Gene Therapy for Ischemic Stroke, P. A. Pechan, M. Fujii, C. Fraefel, Andreas Jacobs, and M. A. Moskowitz. Gene Therapy for the Lysomal Storage Diseases, E. M. Kaye. Gene Therapy for Pain, G. Davar. Gene Therapy of Huntington's Disease, O. Isaesen and N. Haque. Index.

Additional information

NLS9781475753141
9781475753141
1475753144
Gene Therapy for Neurological Disorders and Brain Tumors by E. Antonio Chiocca
New
Paperback
Humana Press Inc.
2013-03-20
458
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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