Foreword. Preface; C.R. Snyder. 1. Physical Illness and Depression in Older Adults: An Introduction; D.R. Shaffer. Part I: Risk Factors. 2. Depression and Disability; M.L. Bruce. 3. Vascular Disease and Depression: Models of the Interplay Between Psychopathology and Medical Comorbidity; J.M. Lyness, E.D. Craine. 4. Pain, Functional Disability, and Depressed Affect; G.M. Williamson. 5. The Role of Everyday Events in Depressive Symptoms for Older Adults; A.J. Zautra, et al. 6. Caregiving and Detrimental Mental and Physical Health Outcomes; J. Bookwala, et al. Part II: Conditioning Variables and Outcomes. 7. Depression, Immune Function, and Health in Older Adults; K.L. Applegate, et al. 8. Quality of Life, Depression, and End-of-Life Attitudes and Behaviors; M. Powell Lawton. 9. The Activity Restriction Model of Depressed Affect: Antecedents and Consequences of Restricted Normal Activities; G.M. Williamson, D.R. Shaffer. 10. We Should Measure Change - And Here's How; C.E. Lance, et al. Part III: Diagnosis and Treatment. 11. Depression and Physicall Illness in Older Primary Care Patients: Diagnostic and Treatment Issues; H.C. Schulberg, et al. 12. The Relationship of Major Depressive Disorder to Alzheimer's Disease; M.F. Weiner, et al. 13. Pharmacotherapy of Geriatric Depression: Taking the Long View; C.F. Reynolds, et al. 14. A Hope-Based Group Treatment for Depressed Older Adult Outpatients; E.J. Klausner, et al. 15. Complex Unity and Tolerable Uncertainly: Relationships of Physical Disorder and Depression; B. Gurland, et al. Part IV: Summary. 16. Physical Illness and Depression in Elderly Adults: A Summary with Implications for Future Directions in Research and Treatment; L.S. Miller.