Kathryn Mannix has spent her medical career working with people who have incurable, advanced illnesses. Starting in cancer care and changing career to become a pioneer of the new discipline of palliative medicine, she has worked in teams in hospices, hospitals and in patients' own homes to deliver palliative care, optimising quality of life even as death is approaching. Having qualified as a Cognitive Behaviour Therapist in 1993, she started the UK's (possibly the world's) first CBT clinic exclusively for palliative care patients, and devised 'CBT First Aid' training to enable palliative care colleagues to add new skills to their repertoire for helping patients.