A charming London neighbourhood is home to Roger and Anita, whose beloved Dalmatians, Pongo and Perdita have become the proud parents of 15 puppies. But when the ghastly Cruella De Vil and her bumbling henchmen, Horace and Jasper unexpectedly appear, the pups swiftly disappear, along with every other Dalmatian puppy in town! Now Pongo and Perdita must rally their animal friends to find Cruella's secret hideaway and free all the puppies.