This is one of the most widely used of the Lecture Notes series. Intended primarily for MRCP candidates, it is also popular with final year medical students and with clinicians reading for higher specialist qualifications. Medical Textbook Review said of the second edition, `Has rapidly rocketed to fame and is already established as a `classic' _ quite deservedly so.' For this new edition the entire text has been extensively revised to take account of the great recent changes in medicine.