New York, 1893, and society portrait painter Piero Piambo feels his artistic ambition waning, even while he immortalizes the city's nouveaux riches in oil paints. But then he receives a bizarre and lucrative commission to paint the mysterious Mrs Charbuque. The catch is that he is not allowed to see her, and so Piambo sits before a screen as his sitter tells him of her life, dreams, and fears -- clues from which he must divine her visage.

As he works, a series of murders plagues the city -- deaths that at first seem accidental. And, as Piambo's masterpiece takes shape, his relationship with Mrs Charbuque grows ever more tangled while her deranged husband becomes hell-bent on some inexplicable vengeance.