The aim of this well established text is to provide a comprehensive, scientific account of pharmacology and a practical guide to the use of drugs as it relates to the practice of clinical anaesthesia. It is of considerable value to candidates sitting the FRCA examination, but will also be of use to any practising anaesthetist wanting to brush up his or her pharmacology knowledge. The book is now in its fourth edition and all chapters have been thoroughly updated with these aims in mind. A conscious decision has been made to re-define this book in order that it remains a concise and useable reference. The purely scientific information has been reduced and reorganised so that the book relates much more to the use of drugs in the clinical setting. ideal for FRCA candidates and those taking other postgraduate anaesthesia exams contains plenty of basic physiology and pharmacology so that supplementary reading is not required international non-proprietary names (rINNs) have been used in preference to British approved names (BANs), far more in keeping with international literature in the field; the book has been shortened slightly since its previous edition to help keep the clinical focus