In The Mind's Eye, Oliver Sacks tells the stories of people who are able to navigate the world and communicate with others despite losing what many of us consider indispensable senses and abilities: the power of speech, the capacity to recognize faces, the sense of three-dimensional space, the ability to read, the sense of sight. For all of these people, the challenge is to adapt to a radically new way of being in the world.

There is Lilian, a concert pianist who becomes unable to read music and eventually even to recognize everyday objects; and Sue, a neurobiologist who has never seen in three dimensions, until she suddenly acquires stereoscopic vision in her fifties.

There is Pat, who, after years of isolation, reinvents herself as an outgoing and highly social member of her community, although she has aphasia and cannot utter a sentence; and Howard, a prolific novelist who must find a way to continue his life as a writer even after a stroke destroys his ability to read.

And there is Dr Sacks himself, who tells the story of his own eye cancer and the bizarre and disconcerting effects of losing vision to one side.

Sacks explores here some very strange paradoxes - people who can see perfectly but not recognize their own children, blind people who become hyper-visual, or who navigate by `tongue vision'. Along the way, he considers more fundamental questions: How do we see? How do we think? How important is internal imagery - or vision, for that matter? Why is it that, although writing is only five thousand years old, humans have a universal, seemingly innate, potential for reading?

The Mind's Eye is a testament to the complexity of vision and the brain and to the power of creativity and adaptation. And it provides a whole new perspective on the power of language and communication, as we try to imagine what it is to see with another person's eyes, or another person's mind.