From the sheep, dog, and cockerel that were sent aloft in Montgolfier's balloon, to Galvani's frog's legs, Dolly the Sheep, the finches of the Galapagos, and even imaginary cats and simulated life forms, Pavlov's Dogs and Schrodinger's Cat explores the fascinating history of the role of living things in science. The ways in which animals and plants have been used in science has always been a matter for considerable public debate, and this book provides an important and fascinating new perspective, setting aside moral reflection to simply examine the history of how and why living creatures have been used for the purposes of scientific discovery. Many extraordinary stories are uncovered throughout five centuries of science - tales of the people involved, curious incidents and episodes, and the occasional scientific fraud too, as clear reflections on the history and philosophy of science are combined with remarkable accounts from the living laboratory.