Conventional theories of neuromuscular block often fail to explain many everyday clinical observations. Scientific progress depends upon questioning the cause of these paradoxes and proposing alternative explanations. Research tests these hypotheses and allows us to seek a preferred explanation of these events. Drawing heavily on his own research experiences over some 35 years, the author has set out to present alternative explanations of everyday experiences in the use of neuromuscular blocking agents in a manner readily understandable to clinical anaesthetists. This is not meant to be a definitive textbook on muscle relaxants. Rather, this book emphasises what is not known and which information (presented as fact) leaves questions unanswered. Much of the book is new information and many of the explanations offered are original; some are controversial. If Neuromuscular Block provokes discussion and causes a measurement of established theories, it will have served its purpose.