This revised edition of the landmark text includes the latest tests and treatments for those who are experiencing unexplained IVF failure, recurrent miscarriage, or long term infertility. An over activated immune response to pregnancy and blood clotting problems are now being identified in women with these previously unexplained conditions. Over half of fertility centers now recommend immune evaluation for women with a history of loss or two or more IVF failures. Centers that specialize in reproductive immunology are seeing success rates of over 85% within three cycles and even saving some couples from expensive and often futile IVF treatment. A fully updated list of all these centers, in the US and abroad, is provided in this book, making this a vital resource for all couples considering fertility treatment and looking for the best options in their area.