This book considers what happens to the body's chemistry when affected by disease. Each chapter explains the principle involved and its application to clinical practice. In addition, there is discussion of diagnostic techniques and specific details about patient management. This book stresses how clinical chemistry relates to the practice of medicine by incorporating over 100 real patient case histories. The text is comprehensive yet succinct and is complemented by 100 illustrations (in full colour for the first time in this new edition). Self assessment material based on clinical vignettes is provided.