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Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, Second Edition Gordon Guyatt

Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, Second Edition von Gordon Guyatt

Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, Second Edition Gordon Guyatt

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Zusammenfassung

A guide to the principles and clinical applications of evidence-based medicine. It demystifies the statistical, analytical, and clinical principles of evidence-based medicine. It shows how to distinguish solid medical evidence from poor medical evidence, and devise strategies for each clinical question.

Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, Second Edition Zusammenfassung

Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, Second Edition Gordon Guyatt

The #1 guide to the principles and clinical applications of evidence-based medicine has just gotten better!

A Doody's Core Title ESSENTIAL PURCHASE for 2011!

No other resource helps you to put key evidence-based medicine protocols into daily clinical practice better than Users' Guides to the Medical Literature.

An instant classic in its first edition, this detailed, yet highly readable reference demystifies the statistical, analytical, and clinical principles of evidence-based medicine, giving you a hands-on, practical resource that no other text can match.

Here, you'll learn how to distinguish solid medical evidence from poor medical evidence, devise the best search strategies for each clinical question, critically appraise the medical literature, and optimally tailor evidence-based medicine for each patient. The new second edition of this landmark resource is now completely revised and refreshed throughout, with expanded coverage of both basic and advanced issues in using evidence-based medicine in clinical practice.

FEATURES:

  • Completely revised and updated to reflect the enormous expansion in medical research and evidence-based resources since the first edition
  • Innovative organization guides you from the fundamentals of using the medical literature to the more advanced strategies and skills for use in every day patient care situations
  • Abundant and current real-world examples drawn from the medical literature are woven throughout, and include important related principles and pitfalls in using medical literature in patient care decisions
  • Practical focus on the key issues in evidence-based practice: What are the results? Are the results valid? How to I apply to results to the care of my patients?
  • More than 60 internationally recognized editors and contributors from the U.S., Canada, South America, Europe, and Asia -- the best of the best in the discipline
  • NEW coverage on how to:
    --Avoid being misled by biased presentations of research findings
    --Interpret the significance of clinical trials that are discontinued early
    --Influence clinician behavior to improve patient care
    --Apply key strategies for teaching evidence-based medicine
  • Also look for JAMAevidence.com, a new interactive database for the best practice of evidence based medicine.

    • Über Gordon Guyatt

    Gordon Guyatt, MD, MSc Departments of Clinical Epidemiology and Biostatistics and Medicine Faculty of Health Sciences McMaster University Hamilton, Ontario Drummond Rennie, MD JAMA, Chicago, IL Philip R. Lee Institute for Health Policy Studies University of California, San Francisco San Francisco, CA Maureen O. Meade, MD, FRCPC, MSc Departments of Medicine and Clinical Epidemiology and Biostatistics Faculty of Health Sciences McMaster University Hamilton, Ontario Deborah J. Cook, MD, MSc Department of Medicine and Clinical Epidemiology and Biostatistics Faculty of Health Sciences McMaster University Hamilton, Ontario

    Inhaltsverzeichnis

    Foreword
    Preface
    Part A. The Foundations
    1.How to Use the Medical Literature-and This Book-to Improve Your Patient Care
    2.The Philosophy of Evidence-Based Medicine
    3.What Is the Question?
    4.Finding the Evidence
    5.Why Study Results Mislead: Bias and Random Error
    Part B. Therapy
    6.Therapy (Randomized Trials)
    7.Does Treatment Lower Risk? Understanding the Results
    8. Confidence Intervals
    9. Advanced Topics in the Validity of Therapy Trials
    9.1 An Illustration of Bias and Random Error
    9.2 Surprising Results of Randomized Trials
    9.3 Randomized Trials Stopped Early for Benefit
    9.4 The Principle of Intention to Treat
    9.5 N-of-1 Randomized Controlled Trials
    9.6 Clinical Decision Support Systems
    10. Advanced Topics in the Results of Therapy Trials
    10.1 Hypothesis Testing
    10.2 Understanding the Results: More About Odds Ratios
    10.3 What Determines the Width of the Confidence Interval?
    10.4 Composite endpoints
    10.5 Measuring Patients' Experience
    11. Advanced Topics in Applying the Results of Therapy Trials
    11.1 Applying Results to Individual Patients
    11.2 Example Numbers Needed to Treat
    11.3 Dealing with Misleading Presentations of Clinical Trial Results
    11.4 Surrogate Outcomes
    11.5 Qualitative Research
    Part C. Harm (Observational Studies)
    12. Harm (Observational Studies)
    13. Advanced Topics in Harm: Correlation and Regression
    Part D. Diagnosis
    14.The Process of Diagnosis
    15. Differential Diagnosis
    16. Diagnostic Tests
    17.Advanced Topics in Diagnosis
    17.1 Spectrum Bias
    17.2 Examples of Likelihood Ratios
    17.3 Measuring Agreement Beyond Chance
    17.4 Clinical Prediction Rules
    Part E. Prognosis
    18.Prognosis
    Part F. Summarizing the Evidence
    19.Summarizing the Evidence
    20. Advanced Topics in Systematic Reviews
    20.1 Reporting Bias
    20.2 Fixed-Effects and Random-Effects Models
    20.3 Making Sense of Variability in Study Results
    20.4 When to Believe a Subgroup Analysis
    Part G. Moving From Evidence to Action
    21.How to Use a Patient Management Recommendation
    22.Advanced Topics in Moving from Evidence to Action
    22.1 Economic Analysis
    22.2 Decision Making and the Patient
    22.3 Moving From Evidence to Action: Recommendations About Screening
    22.4 Grading Recommendations
    22.5 Drug Class Effects
    22.6 Parallel but Separate Goals: Evidence-Based Practitioners and Evidence-Based Care
    22.7 Changing Behavior to Apply Best Evidence in Practice
    22.8 Teachers' Guides to the Users' Guides
    Glossary
    Index

    Zusätzliche Informationen

    GOR013692525
    9780071590341
    007159034X
    Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, Second Edition Gordon Guyatt
    Gordon Guyatt
    Gebraucht - Sehr Gut
    Broschiert
    McGraw-Hill Education - Europe
    2008-07-16
    860
    N/A
    Die Abbildung des Buches dient nur Illustrationszwecken, die tatsächliche Bindung, das Cover und die Auflage können sich davon unterscheiden.
    Dies ist ein gebrauchtes Buch. Es wurde schon einmal gelesen und weist von der früheren Nutzung Gebrauchsspuren auf. Wir gehen davon aus, dass es im Großen und Ganzen in einem sehr guten Zustand ist. Sollten Sie jedoch nicht vollständig zufrieden sein, setzen Sie sich bitte mit uns in Verbindung.