Name: Cardiac Mechano-Electric Feedback and Arrhythmias von Peter Kohl
SKU: 9781416000341
Price: 6.69 EUR
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Cardiac Mechano-Electric Feedback and Arrhythmias Zusammenfassung

Cardiac Mechano-Electric Feedback and Arrhythmias Peter Kohl

Better understand the mechanisms of arrhythmia, cellular modifiers, and the clinical answers to these disorders! Written by internationally recognized leaders in the field, this groundbreaking resource reflects the state of the art in all aspects of mechanical heart function. Readers will find detailed discussions of mechanisms of feedback; effects on cellular electrophysiology; experimental manifestations; normal physiology; pathogenic mechanisms; therapeutic interventions; and, more.

Inhaltsverzeichnis

Introduction * Cardiac mechano-electric interactions and the induction & termination of arrhythmia Fundamental Mechanisms of Cardiac Mechano-Electric Feedback * Cardiac non-selective stretch-activated cation channels: pathophysiological potential * Mechanical modulation of cardiac potassium channels * Cell-volume activated ion channels in cardiac cells * Contribution of cytoskeleton and lipid bi-layer to cellular mechano-reception * The response of cardiac muscle to stretch: role of calcium * Stretch-effects on second messengers and early gene expression Cellular Effects of Mechano-Electric Feedback * Differential effects of stretch on cardiac cells in diastole and systole * Differential effects of stretch and compression of cardiac cells * Mechanical modulation of cardiac non-myocyte structure and function * Mechanical effects on auto- & paracrine signalling in cardiac myocytes and non-myocytes * Stretch effects on connexin expression in cardiac cells Mechano-Electric Feedback in Cardiac Tissue and Whole Heart * Mechanical modulation of sino-atrial pacemaking rate * Stretch effects on atrial conduction and refractoriness * Stretch effects on ventricular conduction and refractoriness * Neuro-humoral modulation of cardiac mechano-electric interactions * Mechanically-induced repolarization dispersion and the mechanical vulnerable period * Experimental arrhythmogenesis by acute mechanical stimulation (Commotio cordis) * Specific stretch-channel blockers: a new class of anti-arrhythmic drugs Clinical Evidence for Cardiac Mechano-Electric Feedback in Man * Non-neuronal component of respiratory sinus arrhythmia * Induction of arrhythmias by precordial impact * Arrhythmogenesis during cardiac catheterisation * Role of transmural gradients in mechano-electric interactions * Hemodynamic unloading and termination of arrhythmias * Bypass-induced ventricular load changes and action potential configuration * Termination of ventricular arrhythmia by acute mechanical interventions Clinical Relevance of Cardiac Mechano-Electric Feedback * Cardiac mechanics and the ECG U-wave * Arrhythmias in ischaemic heart disease in linkage with regional wall motion abnormalities * Arrhythmogenic potential of dysynergy of ventricular mechanics in patients with heart failure and wide QRS complex * Bi-ventricular pacing as a new treatment modality to restore ventricular synchronization * Atrial fibrillation in dilated cardiomyopathy * The angiotensin-renin pathway in left ventricular hypertrophy and SCD * Volume and pressure overload and ventricular arrhythmogenesis * Mortality from heart failure: haemodynamic versus electrical causes * Passive ventricular constraint: new treatment concept for dilated cardiomyopathy * Mechanical modulation of defibrillation efficacy by preload changes * Mechanical advances in cardiopulmonary resuscitation Clinical Trials Evaluating Survival Benefits by Ventricular Unloading or Resynchronization * Effects of bi-ventricular pacing on cardiac mortality and arrhythmias - the Companion trial * InSync Trial * Counter-pulsation and cardiac assist devices. * New intra-ventricular chamber reduction devices (Percutaneous catheter mediated endocardial ventriculoplasty for patients with heart failure). * Ventricular restraint study and reverse re-modeling in patients. * Evolving concepts in measuring ventricular stress-strain relations in the human heart Index

Zusätzliche Informationen

Sku

GOR012392769

ISBN 13

9781416000341

ISBN 10

1416000348

Titel

Cardiac Mechano-Electric Feedback and Arrhythmias Peter Kohl

Autor

Peter Kohl

Zustand

Gebraucht - Sehr Gut

Bindung

Gebundene Ausgabe

Verlag

Elsevier - Health Sciences Division

Datum

20050415

Anzahl der Seiten

448

Preise

N/A

Begleitschreiben

Die Abbildung des Buches dient nur Illustrationszwecken, die tatsächliche Bindung, das Cover und die Auflage können sich davon unterscheiden.

Hinweis

Dies ist ein gebrauchtes Buch. Es wurde schon einmal gelesen und weist von der früheren Nutzung Gebrauchsspuren auf. Wir gehen davon aus, dass es im Großen und Ganzen in einem sehr guten Zustand ist. Sollten Sie jedoch nicht vollständig zufrieden sein, setzen Sie sich bitte mit uns in Verbindung.