Much-acclaimed, this book is now available in paperback. It provides an analytical framework for evaluating public health measures aimed at eradicating or controlling communicable diseases such as malaria, measles, river blindness, sleeping sickness, schistosomiasis, and AIDS. The authors are leaders in the field. Their distinctive contribution has been to show the practice and far-reaching power of mathematical modelling in epidemiology, fully set out here for the first time.