I. INTRODUCTION. 1. The World of the Cell: A Preview. 2. The Chemistry of the Cell. 3. The Macromolecules of the Cell. II. CELL STRUCTURE AND FUNCTION. 4. Cells and Organelles. 5. Bioenergetics: The Flow of Energy in the Cell. 6. Enzymes: The Catalysts of Life. 7. Membranes: Their Structure, Function, and Chemistry. 8. Transport Across Membranes: Overcoming the Permeability Barrier. 9. Intracellular Compartments: The Endoplasmic Reticulum, Golgi Complex, Lysosomes, and Peroxisomes. 10. Beyond the Cell: Junctions, Adhesion, and Extracellular Structures. III. ENERGY FLOW IN CELLS. 11. Chemotrophic Energy Metabolism I: Glycolysis and Fermentation. 12. Chemotrophic Energy Metabolism II: Aerobic Respiration. 13. Phototrophic Energy Metabolism: Photosynthesis. IV. INFORMATION FLOW IN CELLS. 14. The Structural Basis of Cellular Information: DNA, Chromosomes, and the Nucleus. 15. The Cell Cycle, DNA Replication, and Mitosis. 16. Sexual Reproduction, Meiosis, and Genetic Variability. 17. Gene Expression I: The Genetic Code and Transcription. 18. Gene Expression II: Protein Synthesis and Sorting. 19. The Regulation of Gene Expression. V. SPECIFIC CELL FUNCTIONS. 20. Cytoskeletal Structure and Function. 21. Cellular Movement: Motility and Contractility. 22. Signal Transduction Mechanisms I: Electrical Signals in Nerve Cells. 23. Signal Transduction Mechanisms II: Messengers and Receptors. VI. SPECIAL TOPICS IN CELL BIOLOGY. 24. Cellular Aspects of the Immune Response. 25. Cellular Aspects of Cancer. Appendix. Credits. Index.