Section 1: Introduction 1.1: Elizabeth J. Price and Anwar R. Tappuni: Introduction 1.2: Caroline Shiboski and Troy E. Daniels: Historical background, classification and diagnostic criteria 1.3: Simon Bowman: Epidemiology and genetics of Sjogren s Syndrome Section 2: Basic science 2.1: Onorina Berardicurti, Charlotte G. Smith, Roberto Giacomelli, Elizabeth J. Price, and Francesca Barone: Biomarkers in primary Sjogren sSyndrome 2.2: Aurelie Ambrosi, Albin Bjork, and Marie Wahren-Herlenius: Autoantibodies and autoantigens in Sjogren s Syndrome 2.3: Saba Nayar, Serena Colafrancesco, and Francesca Barone: Stromal cells in Sjogren s Syndrome Section 3: Diagnostic investigations 3.1: Anwar R. Tappuni: Clinical assessment of salivary glands function 3.2: Benjamin Fisher: Biopsy gland biopsy procedure and histopathology 3.3: Ashok Adams: Imaging in Sjogren s Syndrome Section 4: Head and neck manifestations and clinical management 4.1: Emily Carter: Salivary glands manifestations and management 4.2: Anwar R. Tappuni: Oral manifestations and management 4.3: Jennifer Fuller and Shakeel Shahdad: Dental related disease Section 5: Ocular manifestations and management 5.1: Nicola Roper, Pasquale Aragona, Maurizio Rolando, and Francisco C Figueiredo: Ocular Manifestations of Sjogren s Syndrome 5.2: Nicola Roper, Pasquale Aragona, Maurizio Rolando, and Francisco C Figueiredo: A therapeutic strategy for Sjogren s Syndrome dry eye Section 6: Systemic manifestations 6.1: Thomas J Tull, Emma Benton, and David D Cruz: Cutaneous involvement and management of Sjogren s Syndrome 6.2: Elizabeth J. Price: Musculoskeletal disease - presentation and management 6.3: Rhys Evans and Stephen Walsh: Renal involvement in Primary Sjogren's Syndrome 6.4: Elizabeth J. Price: Gastrointestinal Disease in Sjogren s syndrome 6.5: Aravind Ganesh, Shane Lyons, and Gabriel Yiin: Neurological complications of Sjogren s Syndrome 6.6: Sara Carty: Cardiovascular and Lung Manifestations of Sjogren s Syndrome 6.7: Coziana Ciurtin and Su-Ann Yeoh: Haematological Manifestations of Sjogren s Syndrome 6.8: Coziana Ciurtin and Su-Ann Yeoh: Fatigue in Sjogren s Syndrome 6.9: Katie Hackett and Helen Cartner: Non-pharmacological interventions for the management of Fatigue and Constitutional Symptoms in Sjogren s Syndrome 6.1: Roberta Priori, Antonina Minniti, and Serena Colafrancesco: Gynaecologic and obstetric aspects in Sjogren s Syndrome 6.11: Saad Rassam: Sjogren s Syndrome Associated Lymphoma Section 7: Juvenile and young adult 7.1: William D. Renton, Elizabeth J. Price, and A.V. Ramanan: Juvenile and young adult onset Sjogren s Syndrome Section 8: Sjogren s mimics and overlaps 8.1: Nurhan Sutcliffe: Mimics of Sjogren s Syndrome 8.2: Nurhan Sutcliffe and Arabella Waller: Sjogren s Syndrome overlaps Section 9: Experimental treatments, emerging therapies and the future 9.1: Benjamin Fisher: Experimental therapies in primary Sjogren s Syndrome 9.2: Elizabeth J. Price and Alan Baer: Sjogren s Syndrome Summary of Clinical Management
