Preface; G. Beek. I. Evolution of Recognition Molecules. 1. New Major Histocompatibility Complex Class IIB Genes From Nurse Shark; S. Bartl. 2. Evolutionary Factors in the Emergence of the Combinatorial Germline Antibody Repertoire; J.J. Marchalonis, et al. 3. Individual-Specific Repertoires of Immune Cells SRCR Receptors in the Purple Sea Urchin (S. Purpuratus); Z. Pancer. II. Cytokines and Antibacterial Peptides of Invertebrates. 4. Molecular Characterization of IL-1-like. Molecules from Lower Vertebrates and Invertebrates; G. Beek, N. Truong. 5. The Detection and Isolation of a Novel Antimicrobial Peptide from the Echinoderm, Cucumaria frondosa; K.A. Beauregard et al. 6. Isolation and Characterization of an IL-1-like Protein from Manduca sexta; N.T. Truong, et al. 7. Clavanins and Styelins, alpha-Helicall Antimicrobial Peptides from the Hemocytes of Styela Clava; R.I. Lehrer et al. 8. The Discovery and Characterization of an Interleukin 6 Cytokine Family Antagonist Protein from a Marine Sponge, Callyspongia sp.; J.V. Peppard, et al. 9. Phylogeny Of Vertebrate Cytokines; C.J. Secombes, et al. 10. Antimicrobial Proteins in Crustaceans; V.J. Smith, J.R.S. Chisholm. 11. Form, Function and Phylogenetic Relationships of Mosquito Immune Peptides; C.A. Lowenberger. III. Cellular and Humoral Responses in Invertebrates. 12. Reactive Oxygen Species and Antimicrobial Defense of Invertebrates: A Bivalve Model; R.S. Anderson. 13. A Role For Protease Inhibitors In Immunity of Long-Lived Animals; P.B. Armstrong, J.P. Quigley. 14. Suppression of the Drosophila Cellular Immune Response By Ganaspis xanthopoda; H. Chiu, et al. 15. Annelid Humoral Immunity: Cell Lysis in Earthworms; E.L. Cooper, et al. 16. Horseshoe Crab Hemocyte-Derived Lectin Recognizing Specific O-Antigens of Lipopolysaccharides; K. Inamori, et al. 17. A Family of C-type Lectins in Manduca sexta; X.-Q. Yu, M.R. Kanost. 18. Role of Tachylectins in Host Defense of the Japanese Horseshoe Crab Tachypieus Tridentatus; S. Kawabata, et al. 19. Hemolytic Capacity, Properties, and Activation Requirements of Cobra Venom Factor-Treated Chicken Serum; T.L. Koppenheffer. 20. Molecular Studies of the Molluscan Response to Digenean Infection; E.S. Loker, Ch.J. Bayne. 21. Insect Lectins and Innate Immunity; S. Natori. 22. Collagenous Lectins in Tunicates and the Proteolytic Activation of Complement; D. Raftos, et al. 23. Immunological Properties of Heat Shock Proteins are Phylogenetically Conserved; J. Robert, et al. 24. Drosophila Cellular Immune System: Dorothy Encodes a UDP Glycosyltransferase; Z. Zhou, et al. 25. Eicosanoids in Insect Immune Signal Transduction; D.W. Stanley, R.W. Howard. 26. Lectins from Tunicates: Structure-Function Relationships in Innate Immunity; G.R. Vasta, et al. IV. Protease Cascades and Invertebrate Host Defenses. 27. Control Mechanisms of the Prophenoloxidase Cascade; M. Sugumaran. 28. Activated Prophenoloxidase Engage