Epidemiology of Chronic Obstructive Pulmonary Disease, Robert A. Wise; Pathology of Emphysema, James C. Hogg; Physiology of Airflow Limitation in Emphysema, Joseph R. Rodarte; Cardiovascular Effects of Emphysema and Lung Volume Reduction Surgery, Steven M. Scharf, Ira Weg and Cesar Keller; Medical Treatment of Chronic Obstructive Pulmonary Disease and Emphysema, Bartolome R. Celli; Pulmonary Rehabilitation and Lung Volume Reduction Surgery, Andrew L. Ries; Evaluation of Patients Considering Lung Volume Reduction Surgery, John J. Reilly Jr ; Radiological Evaluation for Lung Volume Reduction Surgery, Ella Kazerooni; The Interface of Lung Volume Reduction Surgery and Lung Transplantation, Jonathan B. Orens; Anaesthetic Considerations for Lung Volume Reduction Surgery, Philip M. Hartigan and Simon C. Body; Technique of Lung Volume Reduction Surgery, Median Sternotomy Joseph B. Shrager and Larry R. Kaiser; Thoracoscopic Approach for Lung Volume Reduction Surgery, Robert J. McKenna Jr; Perioperative Complications and Their Management, K. Robert Shen and Scott J. Swanson; Surgical Controversies, John Roberts; Bullectomy, Lambros Zellos; Outcomes Following LVRS, Fernando Martinez; Mechanisms of Improvement, Noah Lechtzin and Henry Fessler; Unique Patient Applications, Francis Cordova and Gerard Criner, Financial Aspects of Emphysema and LVRS, Scott Ramsey, Todd Lee and Sean Sullivan; Not the Final Chapter - The National Emphysema Treatment Trial, Gail Weinmann and Alfred Fishman.