PART I: Foundations 1: David J. Weber and William A. Rutala: Biological Basis of Infectious Disease Epidemiology 2: Amy L. Peace-Brewer, Kimberly L. Kane, and James D. Folds: Immune Response and Methods for Detection of Infectious Diseases 3: Dana Loomis and Steve Wing: Theories of Causation 4: M. Elizabeth Halloran: Concepts of Transmission and Dynamics 5: M. Elizabeth Halloran: Overview of Study Design PART II: Data Sources and Measurement 6: D. Peter Drotman and Marc A. Strassburg: Sources of Data 7: Terence L. Chorba: Disease Surveillance 8: Loreen A. Herwaldt, Michael A. Pfaller, and Stefan Weber: Microbial Molecular Techniques 9: Robert H. Fletcher and Scott B. Halstead: Evaluation of Diagnostic Tests PART III: Methods by Transmission Type 10: Jack M. Gwaltney, Jr. and J. Owen Hendley: Respiratory Transmission 11: Karin E. Byers, Richard L. Guerrant, and Barry M. Farr: Fecal-Oral Transmission 12: Frank J. Sorvillo, Amy C. Morrison, O. G. W. Berlin: Vector-borne Transmission 13: James C. Thomas and Sara Stratton: Sexual Transmission PART IV: Outbreak Investigation and Evaluation Research 14: David J. Weber, L. Bernardo Menajovsky, and Richard Wenzel: Investigation of Outbreaks 15: Harry A. Guess and Gary B. Calandra: Clinical Trials 16: James C. Thomas: Community Intervention Studies 17: Robert T. Chen and Walter A. Orenstein: Evaluation of Immunization Programs PART V: Research in Special Populations or Settings 18: Ralph L. Cordell, Larry K. Pickering, and M. Louise Lawson: Research in Out-of-Home Child Care 19: Laura C. Hanson: Infections Among the Elderly 20: Sten H. Vermund, et al.: HIV/AIDS Research 21: Maria J. Wawer: Research Collaborations in Developing Countries Glossary Index