Name: Three-Dimensional Electron Microscopy of Macromolecular Assemblies By Joachim Frank (Investigator, Laboratory of Computational Biology and Molecular Imaging, Investigator, Laboratory of Computational Biology and Molecular Imaging, Howard Hughes Medical Institute)
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Three-Dimensional Electron Microscopy of Macromolecular Assemblies Summary

Three-Dimensional Electron Microscopy of Macromolecular Assemblies: Visualization of Biological Molecules in Their Native State by Joachim Frank (Investigator, Laboratory of Computational Biology and Molecular Imaging, Investigator, Laboratory of Computational Biology and Molecular Imaging, Howard Hughes Medical Institute)

Cryoelectron microscopy of biological molecules is among the hottest growth areas in biophysics and structural biology at present, and Frank is arguably the most distinguished practitioner of this art. CryoEM is likely over the next few years to take over much of the structural approaches currently requiring X-ray crystallography, because one can now get good and finely detailed images of single molecules down to as little as 200,000 MW, covering a substantial share of the molecules of greatest biomedical research interest. This book, the successor to an earlier work published in 1996 with Academic Press, is a natural companion work to our forthcoming book on electron crystallography by Robert Glaeser, with contributions by six others, including Frank. A growing number of workers will employ CryoEM for structural studies in their own research, and a large proportion of biomedical researchers will have a growing interest in understanding what the capabilities and limits of this approach are.

About Joachim Frank (Investigator, Laboratory of Computational Biology and Molecular Imaging, Investigator, Laboratory of Computational Biology and Molecular Imaging, Howard Hughes Medical Institute)

Joachim Frank is an Investigator at the Howard Hughes Medical Institute. He is also Professor of Biomedical Sciences and Adjunct Professor of Biology at the State University of New York at Albany, Adjunct Professor of Biochemistry and Molecular Biophysics at Columbia University, Research Professor of Cell Biology at New York State University Medical School, and head of the Laboratory of Computational Biology and Macromolecular Imaging at Health Research, Inc., the Wadsworth Center.

1: Introduction 2: Electron Microscopy of Macromolecular Assemblies 3: Two-Dimensional Averaging Techniques 4: Multivariate Data Analysis and Classification of Images 5: Three-Dimensional Reconstruction 6: Interpretation of Three-Dimensional Images of Macromolecules Appendix 1: Some Important Definitions and Theorems Appendix 2: Profiles, Point-Spread Functions, and Effects of Commonly Used Low-Pass Filters Appendix 2: Bibliography of Methods Appendix 2: Bibliography of Structures Appendix 2: Special Journal Issues on Image Processing Techniques

Additional information

Sku

NLS9780195182187

ISBN 13

9780195182187

ISBN 10

0195182189

Title

Three-Dimensional Electron Microscopy of Macromolecular Assemblies: Visualization of Biological Molecules in Their Native State by Joachim Frank (Investigator, Laboratory of Computational Biology and Molecular Imaging, Investigator, Laboratory of Computational Biology and Molecular Imaging, Howard Hughes Medical Institute)

Author

Joachim Frank (Investigator, Laboratory of Computational Biology and Molecular Imaging, Investigator, Laboratory of Computational Biology and Molecular Imaging, Howard Hughes Medical Institute)

Condition

New

Binding type

Paperback

Publisher

Oxford University Press Inc

Year published

2006-03-02

Number of pages

432

Prizes

Winner of Joint Winner of the 2017 Nobel Prize in Chemistry.

Cover note

Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

Note

This is a new book - be the first to read this copy. With untouched pages and a perfect binding, your brand new copy is ready to be opened for the first time

Three-Dimensional Electron Microscopy of Macromolecular Assemblies Joachim Frank (Investigator, Laboratory of Computational Biology and Molecular Imaging, Investigator, Laboratory of Computational Biology and Molecular Imaging, Howard Hughes Medical Institute)

Three-Dimensional Electron Microscopy of Macromolecular Assemblies by Joachim Frank (Investigator, Laboratory of Computational Biology and Molecular Imaging, Investigator, Laboratory of Computational Biology and Molecular Imaging, Howard Hughes Medical Institute)

Summary

Three-Dimensional Electron Microscopy of Macromolecular Assemblies Summary

About Joachim Frank (Investigator, Laboratory of Computational Biology and Molecular Imaging, Investigator, Laboratory of Computational Biology and Molecular Imaging, Howard Hughes Medical Institute)

Table of Contents

Additional information

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