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Uses and abuses of medical statistics; design; probability and decision making; data description; from sample to population; correlation and regression; the randomized controlled trial; designed observational studies; common pitfalls in medical statistics. Appendices: notation and hints on calculation; calculation of mean and standard deviation; two sample z-test; two sample t-test; paires t-test; chi-squared test in 2x2 tables; Fisher's exact test; rxc tables; McNemar's test; non-parametric tests; correlation coefficient; linear regression; confidence interval for an odds ration from an unmatched case-control study; calculation and confidence interval of an SMR; sample size calculations; normal probability plots; Kaplan-Meier survival curve and logrank test.