Dr. Lucas Madden is a neuroscientist-turned-FBI profiler who first gained global recognition for cloning the ripper gene and showing its dysfunction in the brains of psychopaths. Later, as an FBI profiler, Madden achieved further notoriety by sequencing the DNA of the world's most notorious serial killers and proposing a controversial "damnation algorithm" that could predict serial killer behavior using DNA alone. Now, a new murderer - the Snow White Killer - is terrorizing women in the Mississippi Delta. When Mara Bliss, Madden's former fiancee, is kidnapped, he must track down a killer who is always two steps ahead of him. Only by entering the killer's mind will Madden ultimately understand the twisted and terrifying rationale behind the murders and have a chance at ending the psychopath's reign of terror.