This first volume of the Handbook serves as a definitive reference source and teaching supplement for the field of regional economics, and for related fields such as geography, transportation economics, regional science and physical planning. It provides an advanced state-of-the-art survey for professional teachers, researchers and advanced (post-) graduate students in these disciplines. In addition to a representative survey of past developments, it also points to new directions and trends within the field. For more information on the Handbooks in Economics series, please see our home page on http://www.elsevier.nl/locate/hes