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Modern Clinical Molecular Techniques Peter Hu

Modern Clinical Molecular Techniques By Peter Hu

Modern Clinical Molecular Techniques by Peter Hu


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Summary

This timely book covers the need to know clinical practices for all those involved in molecular laboratory science.

Modern Clinical Molecular Techniques Summary

Modern Clinical Molecular Techniques by Peter Hu

This timely book covers the need to know clinical practices for all those involved in molecular laboratory science. The field of molecular medicine is evolving at an astounding speed. Propelled by the new insights and technologies, advances are being made at an unprecedented rate. With dual measure given to today's breakthroughs, this book is a collection of the most current practices relevant to the clinical molecular laboratorian. It begins with an introductory section on techniques and procedure. It then presents four separate sections on infectious disease, oncology, pre/post-natal, and identity testing, with specific chapters clearly outlining clinical protocols used in daily practice.

Modern Clinical Molecular Techniques cuts to the heart of what is essential for the practicing molecular laboratory scientist. It is an outstanding resource for those operating within or looking to set up a clinical molecular laboratory.

Table of Contents

Preface

Acknowledgement

Contributors

Section I Current Molecular Laboratory Methods

1 Specimen Collection, Handling and Processing

Lindsy Hengesbach and John Gerlach

2 DNA/RNA Isolation and Quantitation

Jing Wang

3 Test Validation

Cindy McCloskey and S Terence Dunn

4 In Vitro Amplification Methods in Molecular Diagnostics

C. Alexander Valencia and Bradford Coffee

5 Whole Genome Sequencing in the Clinical Laboratory

Tina Hambuch, Brad Sickler, Arnold Liao, Suneer Jain, and Philip D. Cotter

6 Estimation of Exon Dosage Using Real-Time Quantitative Polymerase Chain Reaction

Juliana Purrazzella and Arupa Ganguly

7 Reporting Clinical Molecular Genetic Laboratory Results

Victor Wei Zhang and Lora J. H. Bean

Section II Clinical Molecular Infectious Disease Testing

8 HIV-1 Genotyping and Virtual Phenotyping

Fangling Xu and Jianli Dong

9 COBAS (R) Ampliprep/Taqman HIV-1 Test

Tavat A. Buraruk and Charles E. Stager

10 Hepatitis C Virus (HCV) Genotype Assay (LiPA)

Charles E. Stager and Tavat A. Buraruk

11 COBAS (R) Ampliprep/Taqman HCV Test

Charles E. Stager and Tavat A. Buraruk

12 Epstein-Barr Virus and Cytomegalovirus Viral Load Monitoring by Quantitative Real-Time Polymerase Chain Reaction

Su S. Chen, Seema Hai, and Rajyalakshmi Luthra

13 Quantification of BK Viral Load

Hai Wu and Jianli Dong

14 Molecular Diagnosis and Epidemiology of Rabies

Rodney E. Rohde and Bonny C. Mayes

15 Pyrosequencing for Bacterial Identification

Laura Millecker and Ruth Ann Luna

16 Other Pathogens of Significant Public Health Concern

Chris L. McGowin, Rodney E. Rohde, and Greg C. Whitlock

Section III Clinical Molecular Oncology Testing

17 Gene Rearrangements Testing

Siby Sebastian, Juan Du, and Rizwan Naeem

18 Mutation Analysis in Cancer

Keyur Pravinchandra Patel, John Galbincea, and Rajyalakshmi Luthra

19 Minimal Residual Disease

Wesley Greaves and Rajyalakshmi Luthra

20 Pyrosequencing in Cancer

Bedia A. Barkoh, Rajyalakshmi Luthra, and Shalini Verma

21 Clinical Applications of Microarrays in Cancer

Marilyn M. Li, Ankita Patel, and Xiaofeng Hu

22 Basic Theories and Clinical Applications of Molecular Flow Cytometry

Hua Kang Wu, Hongli Chen, and Peter Hu

Section IV Clinical Molecular Pre/Postnatal Testing

23 Molecular Prenatal Diagnostic Testing

Joanna Wiszniewska and Christine M. Eng

24 PCR Based Diagnosis of Fragile X Syndrome

Daniel J. Dykas and Allen E. Bale

Section V Human Identity Testing

25 Microsatellite Testing Short Tandem Repeat Profile Generation

Robin DeVille Guidry and Laura Gahn

26 Parentage

Laura Gahn and Robin DeVille Guidry

Section VI Clinical Molecular Training

27 Diagnostic Molecular Training

Peter Hu, Patrick A. Lennon, and Madhuri Hegde

28 Molecular Diagnostics Point of Care Testing Training

Chang W. Lee, and Peter Hu

Additional information

NLS9781493941483
9781493941483
1493941488
Modern Clinical Molecular Techniques by Peter Hu
New
Paperback
Springer-Verlag New York Inc.
2016-08-23
436
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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