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Coronaviruses and other Novel Antiviral Targets Summary

Coronaviruses and other Novel Antiviral Targets: Volume 57 by Volume editor Katherine Seley-Radtke (Professor of Chemistry and Biochemistry, University of Maryland, Baltimore County, MD, USA)

Annual Reports in Medicinal Chemistry, Volume 57 in this long-running series, highlights new advances in the field with this new volume presenting interesting chapters on the Mechanism of action of the broadly acting antiviral drug remdesivir, Improving properties of the nucleobase analogue T-706 as a potential anti-SARS-CoV-2 and anti-influenza compound, Antivirals for RNA virus infections Anno 2020-2021, Broad spectrum antiviral fleximer nucleosides, SARS-CoV-2 main protease inhibitors, The search for antivirals to treat alphavirus infections, Inhibitors of Ebola Virus targeting Innate immune evasion, Uracil derivatives as non-nucleoside inhibitors of viral infections, and more.

About Volume editor Katherine Seley-Radtke (Professor of Chemistry and Biochemistry, University of Maryland, Baltimore County, MD, USA)

Prof. Katherine Seley-Radtke groups NIH-funded research employs a chemical biology approach to nucleoside, nucleotide and heterocyclic drug discovery and development with therapeutic emphasis on antiviral, anticancer and antiparasitic targets and overcoming resistance to currently used drugs. Current focus is targeting Ebola, Zika, Dengue and MERS viruses. She has served as the Program Director for UMBCs Chemistry-Biology Interface graduate training program funded by NIH since 2007. This program promotes hands on cross disciplinary research for almost 50 PhD students from four departments at UMBC and UMB. She is currently the Immediate Past President and Secretary-Elect for the International Society of Nucleosides, Nucleotides and Nucleic Acids and a Board member of the International Society for Antiviral Research. Prof. Seley-Radtke also serves as a standing member for several NIH study sections and is an Associate Editor for three scientific journals Antiviral Chemistry & Chemotherapy, Molecules Chemical Biology, and Current Protocols in Chemical Biology.

Table of Contents

1. Improving properties of the nucleobase analogs T-705/T-1105 as potential antivirals 2. Anno 2021: Which antivirals for the coming decade? 3. Broad spectrum antiviral fleximer nucleosides 4. The search for antivirals to treat alphavirus infections 5. Inhibitors of Ebola Virus targeting Innate immune evasion 6. Uracil derivatives as non-nucleoside inhibitors of viral infections

Additional information

NPB9780323915113
9780323915113
0323915116
Coronaviruses and other Novel Antiviral Targets: Volume 57 by Volume editor Katherine Seley-Radtke (Professor of Chemistry and Biochemistry, University of Maryland, Baltimore County, MD, USA)
New
Hardback
Elsevier Science & Technology
2021-11-18
254
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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