Bel Mooney interviews 12 people about the way one particular death has affected their lives. The interviews share the common theme of loss, but remind us that bereavement is at once unique and universal. Chris Patten talks about losing his father and Dan Topolski his mother. Bernard Levin remembers the loss of a friend and Anne Chisholm describes the tragic death of her sister. Alice Thomas Ellis, Barry Rutter and Val Hazel tell of the painful loss of a child. Whilst Lord Hailsham and Pamela Gillilan talk about the death of a beloved spouse. Tony Whitehead describes losing his partner through AIDS and Christopher Booker recalls the murder of his sister.