Part I: Genetics, molecular and cellular biology 1. The neuron navigator 2 gene and Alzheimers diseaseChun Xu, Brenda Bin Su, Stephanie Lozano and Kesheng Wang 2. Interlinking polymorphisms, estrogens, and Alzheimer diseaseLu Hua Chen, Leung Wing Chu and You-Qiang Song 3. Linking EEGs, Alzheimer disease, and the phosphatidylinositol-binding clathrin assembly protein (PICALM) geneNatalya Ponomareva, Tatiana Andreeva, Vitaly Fokin, Sergey Illarioshkin and Evgeny Rogaev 4. CD36 gene polymorphisms and Alzheimers diseaseOmar Sery, Nandu Goswami and Vladimir J. Balcar 5. Genetic contributions to sporadic frontotemporal dementiaJessie S. Carr, Daniel W. Sirkis and Jennifer S. Yokoyama 6. Clinical response to cholinesterase inhibitors in dementia: the role of CYP2D6 and APOE genetic polymorphismsLuis Felipe Jose Ravic de Miranda, Karina Braga Gomes and Paulo Caramelli 7. A1 and A2 purinergic receptor expression in dementiaJ. Mendiola-Precoma, L.C. Berumen, A. Rodriguez-Cruz and G. Garcia-Alcocer 8. Molecular aspects of metallothioneins in dementiasGemma Comes, Anna Escrig, Yasmina Manso, Olaya Fernandez-Gayol, Paula Sanchis, Amalia Molinero, Mercedes Giralt, Javier Carrasco and Juan Hidalgo 9. Implication of microRNAs in Alzheimers disease pathogenesisKatarzyn Marta Zoltowska, Katarzyna Laskowska-Kaszub, Siranjeevi Nagaraj and Urszula Wojda 10. Role of cellular oxidative stress in dementiaGiovanna Galliciotti, Antonella De Jaco, Diego Sepulveda-Falla, Emanuela DAcunto and Elena Miranda 11. Toward an integrative understanding of the neuroinflammatory molecular milieu in Alzheimer disease neurodegenerationJuan M. Zolezzi, Paulina Villaseca and Nibaldo C. Inestrosa 12. Wnt signaling and dementiaCarolina Alquezar and Angeles Martin-Requero 13. Linkage of atypical protein kinase C to Alzheimer diseaseRobert V. Farese and Mini P. Sajan 14. Linking histone deacetylases and phosphodiesterase 5 in novel treatments for Alzheimers diseaseAna Garcia-Osta and Mar Cuadrado-Tejedor 15. Nuclear factor erythroid 2-related factor 2 in Alzheimers diseaseKelsey E. Murphy and Joshua J. Park 16. Implications of alpha- and beta-secretase expression and function in Alzheimers diseaseSven Reinhardt and Kristina Endres 17. Methylation analysis of DNA in Alzheimers diseaseFabio Coppede 18. The signalosome malfunctions in age-associated neuropathologiesRicardo Puertas-Avendano, David Quinto-Alemany, Miriam Gonzalez-Gomez and Raquel Marin 19. FAM3C in Alzheimers disease: a risk-related molecule and potential therapeutic targetMasaki Nishimura, Naoki Watanabe, Emi Hibino, Masaki Nakano, Yachiyo Mitsuishi, Lei Liu and Takuma Sugi 20. Amylin and amylin receptors in Alzheimers diseaseWen Fu and Jack H. Jhamandas 21. Mammalian target of rapamycin complexes: regulation and Alzheimers diseaseHenry Querfurth and Han-Kyu Lee 22. Mammalian target of rapamycin complexes: protein synthesis and autophagy, Parkinsons disease, amyotrophic lateral sclerosis, and frontotemporal dementiaHenry Querfurth and Han-Kyu Lee 23. Linking CD200 in brains and dementia: molecular aspects of neuroinflammationDouglas Gordon Walker Part II: Neurological, physiological and imaging 24. Hippocampal atrophy associated with dementia risk factors and dementiaHiroshi Yao, Yuko Araki, Fumio Yamashita, Makoto Sasaki and Manabu Hashimoto 25. Inflammation and insulin resistance in Alzheimers disease: partners in crimeYuval Nash and Dan Frenke 26. Brain susceptibility to hypoxia/hypoxemia and metabolic dysfunction in Alzheimers disease: insights from animal and in vitro modelsVito Antonio Baldassarro, Andrea Bighinati, Michele Sannia, Luciana Giardino and Laura Calza 27. Neuropeptides and neurolipids: what they are and how they relate to Alzheimers diseaseIvan Manuel, Laura Lombardero, Alberto Llorente-Ovejero and Rafael Rodriguez-Puertas 28. Neurotransmitter receptors in Alzheimers disease: from glutamatergic to cholinergic receptorsLaura Lombardero, Alberto Llorente-Ovejero, Ivan Manuel and Rafael Rodriguez-Puertas 29. A42-a7-like nicotinic acetylcholine receptors and Alzheimers diseaseHoau-Yan Wang and Amber Khan 30. Synaptosomal bioenergetic defects in Alzheimers diseasePamela V. Martino Adami and Laura Morelli 31. Limitations of amyloid imaging in Alzheimers diseaseDavid Weidman 32. Linking gradient echo plural contrast imaging metrics of tissue microstructure with Alzheimer diseaseDmitriy A. Yablonskiy, Tammie L. Benzinger and John C. Morris 33. Hypertensive disorders during pregnancy and later dementia: is there a connection?Ellika Andolf 34. Unraveling the contributions of sleep dysfunction to Alzheimers diseaseElie Gottlieb, Natalie A. Grima, Mark Howard, Amy Brodtmann and Matthew P. Pase Part III: Behaviour and psychopathology 35. Overview of behaviors in dementiaDorothy M. Grillo and Rachel Anderson 36. Delirium superimposed on dementia: a clinical challenge from diagnosis to treatmentMorandi Alessandro, Pozzi Christian, Grossi Eleonora and Bellelli Giuseppe 37. Self-consciousness deficits in dementiaEva M. Arroyo-Anllo and Roger Gil 38. Attentional impairments to novel images in dementiaCelina S. Liu, Michael Rosen, Nathan Herrmann and Krista L. Lanctot 39. Frontal lobe syndrome and dementiasPetronilla Battista, Chiara Griseta, Rosa Capozzo, Madia Lozupone, Rodolfo Sardone, Francesco Panza and Giancarlo Logroscino 40. The stigma of dementiaAlbert Aboseif and Benjamin K.P. Woo 41. Delusions in dementiasMadia Lozupone, Maddalena La Montagna, Antonello Bellomo, Petronilla Battista, Davide Seripa, Antonio Daniele, Antonio Greco, Onofrio Resta, Giancarlo Logroscino and Francesco Panza 42. Linking motor speech function and dementiaMatthew L. Poole and Adam P. Vogel 43. Spatial navigation and Alzheimers diseaseLaura E. Berkowitz, Ryan E. Harvey and Benjamin J. Clark 44. Violence and dementiaG. Cipriani, S. Danti, A. Nuti, L. Picchi and M. Di Fiorino 45. Factors contributing to protection and vulnerability in dementia caregiversFan Zhang, Sheung-Tak Cheng and Manuel Goncalves-Pereira Part IV: Diet, nutrition and environment 46. Nutritional status of dementia and management using dietary taurine supplementationMi Ae Bae and Kyung Ja Chang 47. Selenium and Alzheimers diseaseAdriana Gisele Hertzog da Silva Leme and Barbara R. Cardoso 48. Linking adiponectin and obesity in dementiaMa1gorzata Bednarska-Makaruk 49. The impact of the gut microbiome in Alzheimers disease: cause or consequence?Malena dos Santos Guilherme and Kristina Endres 50. (-)-Epigallocatechin-3-gallate and Alzheimers diseaseLaura Xicota and Rafael de la Torre 51. Lead, cadmium and Alzheimers diseaseKelly M. Bakulski, Howard Hu and Sung Kyun Park Part V: Models and modelling in dementia 52. Alzheimer model 5xfad mice and applications to dementia: transgenic mouse models, a focus on neuroinflammation, microglia, and food-derived componentsTatsuhiro Ayabe and Yasuhisa Ano 53. Use of 192 IgG-saporin as a model of dementia and its applicationJ.W. Chang and Y.S. Park 54. Amyloid beta 1e42-induced animal model of dementia: a reviewJosiane Budni and Jade de Oliveira 55. Resources for the neuroscience of dementiaRajkumar Rajendram and Victor R. Preedy