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Genetics, Neurology, Behavior, and Diet in Dementia Summary

Genetics, Neurology, Behavior, and Diet in Dementia: The Neuroscience of Dementia, Volume 2 by Colin R Martin, RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci (Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK)

Genetics, Neurology, Behavior, and Diet in Dementia: The Neuroscience of Dementia, Volume 2 consolidates different fields of dementia research into a single book, covering a range of subjects, including Alzheimers disease, Lewy body dementia, mixed dementia, vascular dementia, physical activity, risk factors, mortality, biomarkers, SPECT, CT, MRI, questionnaires, nutrition, sleep, delirium, hearing loss, agitation, aggression, delusions, anxiety, depression, hallucinations, psychosis, senile plaques, tau and amyloid-beta, neuroinflammation, and molecular biology. This foundational, comprehensive book assembles the latest understanding on all dementias and their common features in a single source. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field.

About Colin R Martin, RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci (Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK)

Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries. Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at Kings College Hospital and Emeritus Professor of Nutritional Biochemistry at Kings College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at Kings College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.

Table of Contents

Part I: Genetics, molecular and cellular biology 1. The neuron navigator 2 gene and Alzheimers diseaseChun Xu, Brenda Bin Su, Stephanie Lozano and Kesheng Wang 2. Interlinking polymorphisms, estrogens, and Alzheimer diseaseLu Hua Chen, Leung Wing Chu and You-Qiang Song 3. Linking EEGs, Alzheimer disease, and the phosphatidylinositol-binding clathrin assembly protein (PICALM) geneNatalya Ponomareva, Tatiana Andreeva, Vitaly Fokin, Sergey Illarioshkin and Evgeny Rogaev 4. CD36 gene polymorphisms and Alzheimers diseaseOmar Sery, Nandu Goswami and Vladimir J. Balcar 5. Genetic contributions to sporadic frontotemporal dementiaJessie S. Carr, Daniel W. Sirkis and Jennifer S. Yokoyama 6. Clinical response to cholinesterase inhibitors in dementia: the role of CYP2D6 and APOE genetic polymorphismsLuis Felipe Jose Ravic de Miranda, Karina Braga Gomes and Paulo Caramelli 7. A1 and A2 purinergic receptor expression in dementiaJ. Mendiola-Precoma, L.C. Berumen, A. Rodriguez-Cruz and G. Garcia-Alcocer 8. Molecular aspects of metallothioneins in dementiasGemma Comes, Anna Escrig, Yasmina Manso, Olaya Fernandez-Gayol, Paula Sanchis, Amalia Molinero, Mercedes Giralt, Javier Carrasco and Juan Hidalgo 9. Implication of microRNAs in Alzheimers disease pathogenesisKatarzyn Marta Zoltowska, Katarzyna Laskowska-Kaszub, Siranjeevi Nagaraj and Urszula Wojda 10. Role of cellular oxidative stress in dementiaGiovanna Galliciotti, Antonella De Jaco, Diego Sepulveda-Falla, Emanuela DAcunto and Elena Miranda 11. Toward an integrative understanding of the neuroinflammatory molecular milieu in Alzheimer disease neurodegenerationJuan M. Zolezzi, Paulina Villaseca and Nibaldo C. Inestrosa 12. Wnt signaling and dementiaCarolina Alquezar and Angeles Martin-Requero 13. Linkage of atypical protein kinase C to Alzheimer diseaseRobert V. Farese and Mini P. Sajan 14. Linking histone deacetylases and phosphodiesterase 5 in novel treatments for Alzheimers diseaseAna Garcia-Osta and Mar Cuadrado-Tejedor 15. Nuclear factor erythroid 2-related factor 2 in Alzheimers diseaseKelsey E. Murphy and Joshua J. Park 16. Implications of alpha- and beta-secretase expression and function in Alzheimers diseaseSven Reinhardt and Kristina Endres 17. Methylation analysis of DNA in Alzheimers diseaseFabio Coppede 18. The signalosome malfunctions in age-associated neuropathologiesRicardo Puertas-Avendano, David Quinto-Alemany, Miriam Gonzalez-Gomez and Raquel Marin 19. FAM3C in Alzheimers disease: a risk-related molecule and potential therapeutic targetMasaki Nishimura, Naoki Watanabe, Emi Hibino, Masaki Nakano, Yachiyo Mitsuishi, Lei Liu and Takuma Sugi 20. Amylin and amylin receptors in Alzheimers diseaseWen Fu and Jack H. Jhamandas 21. Mammalian target of rapamycin complexes: regulation and Alzheimers diseaseHenry Querfurth and Han-Kyu Lee 22. Mammalian target of rapamycin complexes: protein synthesis and autophagy, Parkinsons disease, amyotrophic lateral sclerosis, and frontotemporal dementiaHenry Querfurth and Han-Kyu Lee 23. Linking CD200 in brains and dementia: molecular aspects of neuroinflammationDouglas Gordon Walker Part II: Neurological, physiological and imaging 24. Hippocampal atrophy associated with dementia risk factors and dementiaHiroshi Yao, Yuko Araki, Fumio Yamashita, Makoto Sasaki and Manabu Hashimoto 25. Inflammation and insulin resistance in Alzheimers disease: partners in crimeYuval Nash and Dan Frenke 26. Brain susceptibility to hypoxia/hypoxemia and metabolic dysfunction in Alzheimers disease: insights from animal and in vitro modelsVito Antonio Baldassarro, Andrea Bighinati, Michele Sannia, Luciana Giardino and Laura Calza 27. Neuropeptides and neurolipids: what they are and how they relate to Alzheimers diseaseIvan Manuel, Laura Lombardero, Alberto Llorente-Ovejero and Rafael Rodriguez-Puertas 28. Neurotransmitter receptors in Alzheimers disease: from glutamatergic to cholinergic receptorsLaura Lombardero, Alberto Llorente-Ovejero, Ivan Manuel and Rafael Rodriguez-Puertas 29. A42-a7-like nicotinic acetylcholine receptors and Alzheimers diseaseHoau-Yan Wang and Amber Khan 30. Synaptosomal bioenergetic defects in Alzheimers diseasePamela V. Martino Adami and Laura Morelli 31. Limitations of amyloid imaging in Alzheimers diseaseDavid Weidman 32. Linking gradient echo plural contrast imaging metrics of tissue microstructure with Alzheimer diseaseDmitriy A. Yablonskiy, Tammie L. Benzinger and John C. Morris 33. Hypertensive disorders during pregnancy and later dementia: is there a connection?Ellika Andolf 34. Unraveling the contributions of sleep dysfunction to Alzheimers diseaseElie Gottlieb, Natalie A. Grima, Mark Howard, Amy Brodtmann and Matthew P. Pase Part III: Behaviour and psychopathology 35. Overview of behaviors in dementiaDorothy M. Grillo and Rachel Anderson 36. Delirium superimposed on dementia: a clinical challenge from diagnosis to treatmentMorandi Alessandro, Pozzi Christian, Grossi Eleonora and Bellelli Giuseppe 37. Self-consciousness deficits in dementiaEva M. Arroyo-Anllo and Roger Gil 38. Attentional impairments to novel images in dementiaCelina S. Liu, Michael Rosen, Nathan Herrmann and Krista L. Lanctot 39. Frontal lobe syndrome and dementiasPetronilla Battista, Chiara Griseta, Rosa Capozzo, Madia Lozupone, Rodolfo Sardone, Francesco Panza and Giancarlo Logroscino 40. The stigma of dementiaAlbert Aboseif and Benjamin K.P. Woo 41. Delusions in dementiasMadia Lozupone, Maddalena La Montagna, Antonello Bellomo, Petronilla Battista, Davide Seripa, Antonio Daniele, Antonio Greco, Onofrio Resta, Giancarlo Logroscino and Francesco Panza 42. Linking motor speech function and dementiaMatthew L. Poole and Adam P. Vogel 43. Spatial navigation and Alzheimers diseaseLaura E. Berkowitz, Ryan E. Harvey and Benjamin J. Clark 44. Violence and dementiaG. Cipriani, S. Danti, A. Nuti, L. Picchi and M. Di Fiorino 45. Factors contributing to protection and vulnerability in dementia caregiversFan Zhang, Sheung-Tak Cheng and Manuel Goncalves-Pereira Part IV: Diet, nutrition and environment 46. Nutritional status of dementia and management using dietary taurine supplementationMi Ae Bae and Kyung Ja Chang 47. Selenium and Alzheimers diseaseAdriana Gisele Hertzog da Silva Leme and Barbara R. Cardoso 48. Linking adiponectin and obesity in dementiaMa1gorzata Bednarska-Makaruk 49. The impact of the gut microbiome in Alzheimers disease: cause or consequence?Malena dos Santos Guilherme and Kristina Endres 50. (-)-Epigallocatechin-3-gallate and Alzheimers diseaseLaura Xicota and Rafael de la Torre 51. Lead, cadmium and Alzheimers diseaseKelly M. Bakulski, Howard Hu and Sung Kyun Park Part V: Models and modelling in dementia 52. Alzheimer model 5xfad mice and applications to dementia: transgenic mouse models, a focus on neuroinflammation, microglia, and food-derived componentsTatsuhiro Ayabe and Yasuhisa Ano 53. Use of 192 IgG-saporin as a model of dementia and its applicationJ.W. Chang and Y.S. Park 54. Amyloid beta 1e42-induced animal model of dementia: a reviewJosiane Budni and Jade de Oliveira 55. Resources for the neuroscience of dementiaRajkumar Rajendram and Victor R. Preedy

Additional information

NPB9780128158685
9780128158685
0128158689
Genetics, Neurology, Behavior, and Diet in Dementia: The Neuroscience of Dementia, Volume 2 by Colin R Martin, RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci (Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK)
New
Hardback
Elsevier Science Publishing Co Inc
2020-11-04
952
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