1. Methodologies to Identify and Analyze Genetic Polymorphisms for Human Histamine Receptors
Stephany Micallef and Astrid Sasse
2. Development, Characterization, and Validation of Anti-Human H3 Receptor Isoform-Specific Antibodies
Fiona C. Shenton, Natasha Lethbridge, and Paul L. Chazot
3. Approaches to Recombinant Histamine H3/H4 Receptor Expression in Mammalian Cells
Tadeusz Karcz, Urszula Cichon, and Katarzyna Kiec-Kononowicz
4. Histamine H2 Receptor Biased Signaling Methods
Natalia Fernandez, Carina Shayo, Carlos Davio, and Federico Monczor
5. Ligand-Binding Kinetics on Histamine Receptors
Reggie Bosma, Tamara A.M. Mocking, Rob Leurs, and Henry F. Vischer
6. Methods to Study the Molecular Pharmacology of the Histamine H4 Receptor
Eleonore W.E. Verweij, Rob Leurs, and Henry F. Vischer
7. Chemiluminescence: A Sensitive Method for Detecting the Effects of Histamine Receptor Agonists/Antagonists on Neutrophil Oxidative Burst
Ondrej Vasicek, Tomas Perecko, Viera Jancinova, Silvia Pazourekova, Radomir Nosal, and Milan Ciz
8. Techniques Used in Pharmacological Evaluation of Histamine H4 Receptor Function on Native Human Eosinophils
Marek Grosicki and Katarzyna Kiec-Kononowicz
9. Assessment of the Efficacy of Histamine Receptor Antagonists in Murine Models of Atopic Dermatitis
Kristine Rossbach, Hanna Koechling, Tomoki Fukuyama, Jenny Wilzopolski, Manfred Kietzmann, and Wolfgang Baumer
10. Methodological Approaches to Study Histamine Pharmacology in the Kidney: From Cell Culture and Cell Imaging to Functional Assays and Electron Microscopy
Alessandro Pini, Eleonora Veglia, Cristina Grange, and Arianna Carolina Rosa
11. Histamine and the Kidney: In Vivo Animal Models
Alessandro Pini, Eleonora Veglia, and Arianna Carolina Rosa
12. Methodological Approaches to Investigate the Effects of Histamine Receptor Targeting Compounds in Preclinical Models of Breast Cancer
Diego J. Martinel Lamas, Melisa B. Nicoud, Helena Sterle, Graciela P. Cricco, Gabriela A. Martin, Graciela A. Cremaschi, Hubert G. Schwelberger, Elena S. Rivera, and Vanina A Medina
13. Evaluation of Histidine Decarboxylase (HDC) Activity and Human Histamine Receptor 3 (H3R) and HDC mRNA Levels
Carlos Acosta-Andrade, Jose L Urdiales, Ignacio Fajardo, and Francisca Sanchez-Jimenez
14. Cerebrospinal Fluid Markers in Neuroinflammation: The Paradigm of Optic Neuritis
Dimitrios P. Besinis and Maria C. Anagnostouli
15. In Vivo Diagnostic Procedures for IgE-Mediated Allergic Disorders
Christopher Koulias, Xenophon Aggelides, Caterina Chliva, and Michael Makris
16. Dermatological Indications of Antihistamines
Chrysovalantis Korfitis, Efstathios Rallis, and Dimitrios Rigopoulos
17. Histamine Quantification in Human Blood Samples
Ekaterini Tiligada, Maria Kakolyri, and Madeleine Ennis