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Advances in Immunology Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)

Advances in Immunology By Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)

Summary

Presents the developments as well as comprehensive reviews in immunology. This title includes articles that address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities.

Advances in Immunology Summary

Advances in Immunology: Volume 105 by Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future.

Advances in Immunology Reviews

"The series which all immunologists need." --The Pharmaceutical Journal "Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions." --Science "Deserves a permanent place in biomedical libraries as an aid in research and in teaching." --Journal of Immunological Methods

About Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

Table of Contents

Learning from leprosy: insight into the human innate immune response Dennis Montoya and Robert L. Modlin 2. The immunological functions of saposins Alexandre Darmoise, Patrick Maschmeyer and Florian Winau OX40-OX40 ligand interaction in T cell-mediated immunity and immunopathology Naoto Ishii, Takeshi Takahashi, Pejman Soroosh, and Kazuo Sugamura 4.The family of IL-10-secreting CD4+ T cells Keishi Fujio, Tomohisa Okamura, and Kazuhiko Yamamoto 5.Artificial engineering of secondary lymphoid organs Jonathan K.H. Tan and Takeshi Watanabe 6. Aid And Somatic Hypermutation Robert W. Maul and Patricia J. Gearhart 7. BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis Katia Basso and Riccardo Dalla-Favera

Additional information

NPB9780123813022
9780123813022
0123813026
Advances in Immunology: Volume 105 by Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)
New
Hardback
Elsevier Science Publishing Co Inc
2010-07-22
236
N/A
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