Part 1 H.pylori - the micro-organism: history links micro-organisms and ulcers; the discovery of H.pylori; the scale of the problem; epidemiology; transmission of H.pylori; pathogenic characteristics of H.pylori; the host response to infection. Part 2 H.pylori - the clinical problem: classification of gastritis; H.pylori, gastritis and non-ulcer dyspepsia; H.pylori and peptic ulcer disease - duodenal infection, gastric ulceration, evidence linking H.pylori with peptic ulceration; H.pylori and gastric cancer; H.pylori in children. Part 3 Management of H.pylori infection: detection of H.pylori; direct tests - endoscopy, histology, bacteriological culture, indirect tests - biopsy urease test, urea breath test, serology tests, treating H.pylori infection, monotherapy - bismuth, urease inhibitors, antibiotic monotherapy, acid-suppressants, honey, dual therapy - bismuth and metronidazole, omeprazole and amoxycillin, omeprazole and clarithromycin, triple therapy - bismuth triple therapy, acid-suppressant triple therapy - future treatments, eradication or suppression?; who should receive treatment? Part 4 Managing dyspeptic conditions in the H.pylori era: patients with peptic ulceration - H.pylori eradication, suggested H.pylori eradication treatment for patients with duodenal ulcer disease; patients with dyspepsia; where are we going in the future?
