Cart
Free Shipping in the UK
Proud to be B-Corp

Models for Assessing Drug Absorption and Metabolism Ronald T. Borchardt

Models for Assessing Drug Absorption and Metabolism By Ronald T. Borchardt

Models for Assessing Drug Absorption and Metabolism by Ronald T. Borchardt


£203.29
Condition - New
Only 2 left

Summary

Pharmaceutical scientists in industry and academia will appreciate this single reference for its detailed experimental procedures for conducting biopharmaceutical studies. This well-illustrated guide allows them to establish, validate, and implement commonly used in situ and in vitro model systems.

Models for Assessing Drug Absorption and Metabolism Summary

Models for Assessing Drug Absorption and Metabolism by Ronald T. Borchardt

Pharmaceutical scientists in industry and academia will appreciate this single reference for its detailed experimental procedures for conducting biopharmaceutical studies. This well-illustrated guide allows them to establish, validate, and implement commonly used in situ and in vitro model systems. Chapters provide ready access to these methodologies for studies of the intestinal, buccal, nasal and respiratory, vaginal, ocular, and dermal epithelium as well as the endothelial and elimination barriers.

Table of Contents

General Principles in the Characterization and Use of Model Systems for Biopharmaceutical Studies; R.T. Borchardt, et al. Methods for Evaluating Intestinal Permeability and Metabolism in vitro; P.L. Smith. Culturedintestinal Epithelial Cell Models; I.J. Hidalgo. Intestinal Rings and Isolated Intestinal Mucosal Cells; J.A. Fix. Models of Drug Absorption in situand in Conscious Animals; R. Griffiths, et al. Model Systems for Intestinal Lymphatic Transport Studies; C.J.H. Porter, W.N. Charman. Buccal Tissues and Cell Culture; E. Quadros, et al. Isolated Hepatocytes; M. Vore, et al. Cultured Rat Hepatocytes; E.L. Le Cluyse, et al. Isolated Perfused Liver; K.L.R. Brouwer,R.G. Thurman. Isolated Renal Brush Border and Basolateral Membrane Vesicles and Cultured Renal Cells; M.M. Gutierrez, et al. Use of an Isolated Perfused Kidney to Assess Renal Clearance of Drugs: Information Obtained in Steadystate and Nonsteady State Experimental Systems; N. Okudaira, Y. Sugiyama. Brain Microvessel Endothelial Cell Culture Systems; K.L. Audus, et al. Methods to Study Drug Transport in Isolated Choroid Plexus Tissue and Cultured Cells; C.B. Washington, et al. Brain Perfusion Systems for Studies of Drug Uptake and Metabolism in the Central Nervous System; Q.R. Smith. 8 additional articles. Index.

Additional information

NPB9780306452437
9780306452437
030645243X
Models for Assessing Drug Absorption and Metabolism by Ronald T. Borchardt
New
Hardback
Springer Science+Business Media
1996-08-31
444
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a new book - be the first to read this copy. With untouched pages and a perfect binding, your brand new copy is ready to be opened for the first time

Customer Reviews - Models for Assessing Drug Absorption and Metabolism