Cart
Free Shipping in the UK
Proud to be B-Corp

The Cardiovascular Glycocalyx in Health and Disease Summary

The Cardiovascular Glycocalyx in Health and Disease: Volume 91 by Volume editor Ibra S. Fancher (Assistant Professor, Department of Kinesiology and Applied Physiology, University of Delaware, College of Health Sciences, DE, USA)

The Cardiovascular Glycocalyx in Health and Disease, Volume 91 gives updates on the glycocalyx function through the cardiovascular system and its integration in whole system physiology. Chapters address Endothelial surface layers in the kidney, Pharmacological targeting of the glycocalyx -- current status and prospects, The endothelial glycocalyx and the subtleties of female microcirculation, and much more targeted content.

About Volume editor Ibra S. Fancher (Assistant Professor, Department of Kinesiology and Applied Physiology, University of Delaware, College of Health Sciences, DE, USA)

Dr. Fancher is an Assistant Professor at the University of Delaware in the Department of Kinesiology and Applied Physiology, College of Health Sciences. Dr. Fancher's immediate interests are in understanding how cardiovascular risk factors, such as obesity, impair vascular endothelial ion channel function which ultimately results in dysregulation of vascular function. His recent studies have detailed a link between damage to the endothelial glycocalyx and impaired K+ channel function in obesity; a mechanism he proposes contributes to obesity-induced vascular dysfunction. Ongoing studies in the lab are focused on determining the mechanistic link between elevated macronutrients associated with a poor Western diet and obesity, disruption of the glycocalyx, and K+ channel function. Dr. Andreia Z. Chignalia is an Assistant Professor at the University of Arizona, Department of Anesthesiology, College of Medicine-Tucson. The research in the Chignalia lab focuses on studying the redox mechanisms underlying cardiovascular diseases and associated pulmonary complications. Special emphasis is given to explore the differential redox-sensitive pathways activated by individual glycocalyx components during disease progression. Her research program utilizes a broad range of techniques that span from in vitro, in situ, and in vivo animal models of disease with a translational approach to advance the understanding of human disease with the goal to identify new targets for drug development.

Table of Contents

1. Impairment of endothelial glycocalyx in atherosclerosis and obesity Sang Joon Ahn, Elizabeth Le Master, Sara T. Granados and Irena Levitan 2. The glycocalyx and calcium dynamics in endothelial cells Cameron M. Mortazavi, Jillian M. Hoyt, Aamir Patel and Andreia Z. Chignalia 3. Mechanotransduction and the endothelial glycocalyx: Interactions with membrane and cytoskeletal proteins to transduce force Hassan Askari, Masoumeh Sadeghinejad and Ibra S. Fancher 4. Setting the stage for universal pharmacological targeting of the glycocalyx Karim Almahayni and Leonhard Moeckl 5. The effects of female sexual hormones on the endothelial glycocalyx Simone R. Potje, Nubia S. Martins, Maira N. Benatti, Daniel Rodrigues, Vania L. D. Bonato and Rita C. Tostes 6. The role of hyaluronan in endothelial glycocalyx and potential preventative lifestyle strategy with advancing age Jisok Lim, Daniel R. Machin and Anthony J. Donato

Additional information

NPB9780443191596
9780443191596
044319159X
The Cardiovascular Glycocalyx in Health and Disease: Volume 91 by Volume editor Ibra S. Fancher (Assistant Professor, Department of Kinesiology and Applied Physiology, University of Delaware, College of Health Sciences, DE, USA)
New
Hardback
Elsevier Science Publishing Co Inc
2023-04-11
166
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a new book - be the first to read this copy. With untouched pages and a perfect binding, your brand new copy is ready to be opened for the first time

Customer Reviews - The Cardiovascular Glycocalyx in Health and Disease