In this issue of Anesthesiology Clinics, guest editors Drs. Zdravka Zafirova and Richard D. Urman bring their considerable expertise to the topic of Preoperative Patient Evaluation. Top experts in the field discuss this important opportunity to identify co-morbidities that may lead to patient complications during the anaesthetic, surgical, or post-operative period, including anticoagulation preop management and regional anesthesia recent updates/guidelines; marijuana use and vaping; enhanced recovery pathways: preoperative considerations in children; management of preoperative anemia; and more. Contains 17 relevant, practice-oriented topics including what's new in preop cardiac testing; virtual preoperative evaluation process: a new paradigm; newer hypoglycemic medications; new therapies for heart failure and pulmonary hypertension; preoperative management of the adult patient with cancer; and more. Provides in-depth clinical reviews on preoperative patient evaluation, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.