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The Infectious Microbe Bill Firshein (Emeritus Professor of Biology, Emeritus Professor of Biology, Wesleyan University)

The Infectious Microbe By Bill Firshein (Emeritus Professor of Biology, Emeritus Professor of Biology, Wesleyan University)

Summary

Discusses the basic characteristics of infection and the spread of viruses and bacteria, using case studies of six critical diseases.

The Infectious Microbe Summary

The Infectious Microbe by Bill Firshein (Emeritus Professor of Biology, Emeritus Professor of Biology, Wesleyan University)

Of the almost innumerable interactions between science and humanity, few are as central or as significant as microorganisms. These single-celled complete living organisms are intimately involved with life and must be taken into account in many ways when considering the welfare and health of the public. Though microorganisms have major impacts on many chemical and ecological processes, they are most often recognized for their ability to cause serious and sometimes fatal diseases. From diseases caused by bacteria like pneumonia, tuberculosis, anthrax, meningitis, typhoid, and bubonic plague, to diseases caused by viruses like HIV, polio, yellow fever, hepatitis, and influenza, humanity has struggled to cope with their rapidly changing capabilities. This book is a response to current confusion and misunderstanding of microbes amongst the general public; written in narrative form, it will allow readers to better understand the scientific concepts and terminology of how microbial or viral diseases are caused, to ask intelligent questions about the impact of such diseases on our wellbeing, and to comprehend reports about disease outbreaks that flood the media. Following several introductory chapters that introduce the microbe, its history, and the necessary fundamental chemical and biological concepts, the heart of the book describes in great detail six critical microbial and viral diseases that plague our world and how each of them illustrates the basic characteristics of infection. Each of these six diseases follows the same path-invasion, internal spread, toxin effects, and excretion-and an understanding of the pathogenicity of each will provide readers with a better understanding of the fascinating scientific relationship between man and virus, human and microbe, and how to live with or defeat them.

The Infectious Microbe Reviews

In this little treasure, Professor Firshein has used his 50-year career as a teacher of science and non-science students alike to distill this timely subject down to its essence. Utilizing an infectious journalistic style throughout, Firshein alternates between basic and applied coverage of this topic with effective case studies to fortify his message and grip on the reader. The result is a timely and compelling book that can be read by all, which should impact the next generation of citizens charged with understanding the nature of the infectious disease and crafting a sensible and strategic health care policy for our 21st-century world. -- Donald Oliver, Daniel Ayres Professor of Biology, Wesleyan University The Infectious Microbe by Bill Firshein cogently presents the background and challenge of minute organisms that have both detrimental and beneficial effects in nature. Experts and newcomers to this fascinating field of visually undetectable organisms will understand the conflict between microbes and their hosts. They will gain great insight into life in a micro-universe and enjoy the drama that unfolds as viruses and bacteria emerge, some very recently, and play roles in the ultimate survival of species on earth. -- Jay Levy, Professor of Medicine, University of California, San Francisco This is an engaging journey into the world of pathogens. The microbial world is unimaginably huge, universally prevalent and diverse. Dr. Firshein provides the reader of this fascinating book with a practical level of understanding of this world, presented in a most comfortable conversational style. It is a must-read for everyone at all concerned with their personal, family and community health and with national and global health policies, or who has simply wondered about the nature of the infectious diseases to which we are all susceptible. -- Thomas Broker, Professor of Biochemistry, University of Alabama at Birmingham Featured in The Quarterly Review of Biology

About Bill Firshein (Emeritus Professor of Biology, Emeritus Professor of Biology, Wesleyan University)

Bill Firshein is professor and chair of the biology department at Wesleyan University.

Table of Contents

PREFACE ; CHAPTER 1. INTRODUCTION TO THE INFECTIOUS MICROBE ; A. The Scope of Microbial Life and Infectious Diseases ; B. What Is a Pathogen? ; C. The Relationship Between a Pathogen and the Host It Infects Is Complex and Varied ; D. Susceptibility and Virulence Factors Are Closely Related ; E. Major Groups of Pathogens Are Found Throughout the Microbial World ; CHAPTER II. FUNDAMENTAL CONCEPTS OF BIOLOGY AND CHEMISTRY HELP UNDERSTAND PATHOGENICITY ; A. Genetics: The Nature of the Gene and Its Chemical Structure (DNA) ; B. Metabolism Consists of Chemical Reactions Without Which Life Would Not Exist ; C. Biological Catalysts (Enzymes) Mediate Every Chemical Reaction in the Cell ; D. Genes Control the Synthesis and Expression of Enzymes (Which Are Proteins) and Hence Control the Functioning of the Cell ; E. The Mechanism of Protein Synthesis Involves a Complex Series of Metabolic Reactions and Cellular Organelles Starting with DNA, a Related Macromolecule, RNA, and the Ribosome (the Protein Synthesizing Factory) ; F. Gene Expression is Tightly Regulated to Economize and Preserve Cell Integrity ; G. Genetic Modifications in the Process of Gene Expression in Microbes Are Varied and Complex. They Include Mutations, Transfer Transformation (Recombination) of Genes From One Cell to Another, and Many Other Variations of These Events ; H. Modern Technologies ; CHAPTER III. HISTORY OF MICROBIOLOGY ; A. Voices in the Wilderness ; B. The Golden Age and Modern Era ; CHAPTER IV. EMERGING AND REEMERGING DISEASES ; A. Introduction ; B. Definitions ; C. Examples of Each ; D. Role of Antibiotics ; CHAPTER V. CASE HISTORIES ; A. Introduction: Why Are the Following Examples Chosen? ; B. HIV-AIDS - The Plague That Threatens Modern Society ; 1) Origins ; 2) Characteristics ; 3) Versatility ; 4) Structure of Genome ; 5) Treatment ; 6) Course of Infection ; 7) Conclusions ; C. Tuberculosis - The White Plague, Ancient, But Still Lethal ; 1) Introduction ; 2) Description ; 3) Pathogenicity ; 4) Testing and Virulence Factors ; 5) Treatment ; D. Streptococci and Staphylococci: More Intimacy Than We Desire ; 1) Introduction ; 2) General Descriptions ; 3) Staphylococci ; 4) Toxins ; 5) Staph Diseases ; 6) Treatment ; 7) Streptococci ; 8) Toxins ; 9) Other Streptococci ; E. Ulcers and Helicobacter - The Uncommon Pathogen ; 1) Introduction ; 2) The Organism ; 3) The Disease ; 4) Pathogenicity ; 5) Toxins ; 6) Treatment ; F. Cholera - A Pretty Nasty Beast ; 1) Introduction ; 2) The Organism ; 3) Pathogencity ; 4) Diagnosis, Prevention and Treatment of Cholera ; 5) The Agony of Haiti ; 6) Conclusions ; G. Influenza - Bird Flu, Swine Flu and All That Jazz ; 1) Introduction ; 2) The Virus and Pathogenicity ; 3) Spread, Prevention and Treatment ; 4) Conclusion ; CHAPTER VI. BIOFILMS: CITY OF MICROBES AND THEIR ROLE IN PATHOGENCITY ; A. Introduction ; B. Biofilms and Infectious Diseases ; CHAPTER VII. BIOLOGICAL TERRORISM - MYTHS AND REALITIES ; A. Introduction ; B. Historical Perspective ; C. Bioterrorism Today: State of the Art and Preparedness ; D. Conclusions ; GLOSSARY ; A. Scientists ; B. Definitions ; PHOTO CREDITS

Additional information

GOR012777175
9780199329618
0199329613
The Infectious Microbe by Bill Firshein (Emeritus Professor of Biology, Emeritus Professor of Biology, Wesleyan University)
Used - Very Good
Hardback
Oxford University Press Inc
20140227
176
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a used book - there is no escaping the fact it has been read by someone else and it will show signs of wear and previous use. Overall we expect it to be in very good condition, but if you are not entirely satisfied please get in touch with us

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