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StructureActivity Relationships in Environmental Sciences M. Nendza

StructureActivity Relationships in Environmental Sciences By M. Nendza

StructureActivity Relationships in Environmental Sciences by M. Nendza


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Summary

Structure-Activity Relationships in Environmental Science is the first book of its kind that brings together information from a variety of sources into one document. Part One covers the theoretical background of structure-activity studies and Part Two deals with the practical applications of such methods in the environmental sciences.

StructureActivity Relationships in Environmental Sciences Summary

StructureActivity Relationships in Environmental Sciences by M. Nendza

Structure-Activity Relationships in Environmental Science is the first book of its kind that brings together information from a variety of sources into one document. It provides a comprehensive overview of the entire field of quantitative structure-activity relationships (QSARs) as well as being a reference for SAR experts.
The book comprises three parts. Part One covers the theoretical background of structure-activity studies and Part Two deals with the practical applications of such methods in the environmental sciences. Part Three critically discusses SAR models with respect to their reliability and their aptness in environmental hazard and risk assessment. Recommendations are made as to which model to use and the case is presented for using QSARs in hazard assessment.
The use of QSARs is becoming increasingly important since there is little experimental data available on environmentally relevant chemicals. Structure-Activity Relationships in Environmental Sciences will thus serve as an invaluable guide to both postgraduate and research scientists as well as professional ecologists.

Table of Contents

One Theoretical Background.- 1 Descriptors of the chemical structures.- 2 Activity and effects parameters.- 3 Statistical methods.- Two Application of QSARs in Environmental Sciences.- 4 Exposure-related parameters.- 5 Effects-related parameters.- 6 Validation status of QSAR models for exposure-and effects-related parameters.- Three Application of QSARs in Environmental Hazard and Risk Assessments.- 7 Assessments of chemical mixtures.- 8 Interspecies correlations.- 9 Application of QSAR estimates in hazard evaluation and risk assessment.- Appendix: QSAR-related computer programs and software.- References and bibliography.

Additional information

NPB9780412564307
9780412564307
0412564300
StructureActivity Relationships in Environmental Sciences by M. Nendza
New
Hardback
Chapman and Hall
1997-12-31
269
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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