Name: Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders By Adeboye Adejare (Professor, Pharmaceutical Sciences, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA)
SKU: 9780128028100
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Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders Summary

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer's Disease by Adeboye Adejare (Professor, Pharmaceutical Sciences, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA)

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimers Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimers Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimers Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimers Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders.

About Adeboye Adejare (Professor, Pharmaceutical Sciences, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA)

Adeboye Adejares research group is interested in the areas of design and syntheses of small organic molecules to probe neurodegeneration, especially Alzheimers disease, and for treatment of cancer. They are also interested in in vitro models of drug absorption and ability to cross blood brain barrier; drug targeting; pharmaceutical profiling; and chemistry of fluoroaromatic compounds. The research is funded by the National Institutes of Health, the Office of Naval Research, and several pharmaceutical companies. These efforts have resulted in over 50 publications, 5 patents, and over 100 presentations at meetings, including invited presentations at national and international conferences. He also serves on several national panels, including those by NIH, NSF, and Alzheimers Association. Dr. Adejare is the editor of Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimers Disease which is also published by Elsevier.

1. General description of neurodegenerative disorders 2. Alzheimers disease diagnosis 3. National plan and resources to address Alzheimers disease 4. Current Medications for Treatment of Alzheimer's Disease: Acetylcholine esterase inhibitors and NMDA receptor antagonist 5. Physicochemical properties for potential AD drugs 6. Receptor approaches 7. Amyloid hypothesis 8. Tau proteins 9. Cholesterol and fat metabolism 10. Energy Metabolism 11. Simple in vivo models of Neurodegeneration (C. Elegans, fruitfly, and similar models) 12. Rodent Models 13. Clinical Trials 14. Non-pharmacologic Treatment Approaches

Additional information

Sku

NPB9780128028100

ISBN 13

9780128028100

ISBN 10

0128028106

Title

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer's Disease by Adeboye Adejare (Professor, Pharmaceutical Sciences, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA)

Author

Adeboye Adejare (Professor, Pharmaceutical Sciences, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA)

Condition

New

Binding type

Hardback

Publisher

Elsevier Science Publishing Co Inc

Year published

2016-10-04

Number of pages

316

Prizes

N/A

Cover note

Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

Note

This is a new book - be the first to read this copy. With untouched pages and a perfect binding, your brand new copy is ready to be opened for the first time

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders Adeboye Adejare (Professor, Pharmaceutical Sciences, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA)

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders by Adeboye Adejare (Professor, Pharmaceutical Sciences, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA)

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders Summary

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer's Disease by Adeboye Adejare (Professor, Pharmaceutical Sciences, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA)

About Adeboye Adejare (Professor, Pharmaceutical Sciences, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA)

Table of Contents

Additional information

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