Section I. History of Fetal and Neonatal Intensive Care Chapter 1. The Fetus as a Patient (Wapner) Chapter 2. The Neonate as a Patient (Spitzer) Section II. Fetal Development Chapter 3. The Genetics of Development and Common Genetic Problems (Parton, Anderson) Chapter 4. Environmentally Induced Birth Defects (Vaux, Chan, Jones) Section III. Fetal Diagnosis Chapter 5. Ultrasound Evaluation of the Uncomplicated Pregnancy (Garry, Figueroa) Chapter 6. Amniocentesis (Wapner, Trauffer, Johnson) Chapter 7. Chorionic Villus Sampling (Wapner) Section IV. Assessing Fetal Well Being Chapter 8. Identification and Management of the Fetus at Risk for Hypoxemia and Acidosis (Quirk, Figueroa, Al Khabbaz) Chapter 9. The Fetal Biophysical Profile (Elimian) Chapter 10. Amniotic Fluid Markers of Fetal Lung Maturity (Geary, Whitsett) Section V. Fetal Intevention Chapter 11. Intrauterine Growth Restriction (Subhani) Chapter 12. Hydrops Fetalis (Coulter) Chapter 13. Fetal Metabolic and Hormonal Defects (Evans, Rosner, Shahar, Yaron) Chapter 14. Stem Cells and Gene Therapy (Haneline, Yoder) Chapter 15. Pharmacology in the Fetus and Newborn (Aranda) Chapter 16. The Surgery of Fetal Malformations (Harrison, Lee H) Chapter 17. Multifetal Pregnancy Reduction and Selective Termination (Wapner) Chapter 18. Tocolytic Therapy and Preterm Labor (Lowery, Reece) Section VI. Maternal Factors Influencing Neonatal Outcome Chapter 19. Maternal Illness and the Effects on the Fetus (Burke, Becker) Chapter 20. Diabetes During Pregnancy (Garry) Chapter 21. Gestational Hypertension and Pre-eclampsia (Hnat, Sibai) Chapter 22. Oligohydramnios and Polyhydramnios (Phelan) Chapter 23. Substance Use During Pregnancy (Hurt) Section VII. Management Considerations in The High Risk Pregnancy Chapter 24. Preterm Labor (Figueroa R, Ogburn) Chapter 25. Premature Rupture of Membranes-Diagnosis and Management (Chan, Khandewal, Hammes) Chapter 26. Maternal Fever and Chorioamnionitis (Smith, Weiner) Chapter 27. Meconium and the Compromised Fetus and Neonate (Fuloria, Wiswell) Chapter 28. Third Trimester Hemorrhage (Lewis, Broth, Bolognese) Chapter 29. Management of Multiple Gestations (Skupski, Chervenack) Section VIII. Neonatal Resuscitation Chapter 30. Delivery Room Resuscitation (Donn, Faix) Chapter 31. Examination of the Critically III Neonate (Wiswell, Spizter) Section IX. Intensive Care Of Neonates: General Considerations Chapter 32. Radiology in the Intensive Care Nursery (Gross) Chapter 33. Fetal and Neonatal Thermal Regulation (Chandra, Baugart) Chapter 34. Neonatal Nurse Practitioners in the Neonatal Intensive Care Unit (Mele, Herbert) Section X. Pulmonary Disease in the Neonate Chapter 35. Blood Gas Interpretation (Kornhauser) Chapter 36. Apnea (DeCristofaro) Chapter 37. Sudden Infant Death Syndrome (Hunt) Chapter 38. Differential Diagnosis of Neonatal Respiratory Disorders (Solarin, Zubrow, Delivoria-Papodapolus) Chapter 39. Persistent Pulmonary Hypertension and Inhalational Pulmonary Vasodilators (Steinhorn, Porta) Chapter 40. Pulmonary Function Testing in the Sick Newborn (Bhutani, Sivieri) Chapter 41. Neonatal Bronchoscopy (Finer) Chapter 42. Oxygen Therapy (Weis, Cox, Fox) Chapter 43. Continuous Positive Airway Pressure (Weis, Cox, Fox) Chapter 44. Positive-Pressure Ventilation: The Use of Mechanical Ventilation in the Treatment of Neonatal Disease-General Principles of Care (Spitzer) Chapter 45. High-Frequency Jet Ventilation (Keszler) Chapter 46. High-Frequency Oscillatory Ventilation (Cotton, Clark) Chapter 47. Modern Extracorporeal Membrane Oxygenation for the Human Newborn Infant (Chandra, Baumgart) Chapter 48. Liquid Ventilation (Shaffer, Oliver, Wolfson M, Greenspan) Chapter 49. Airleak (Cotton, Goldberg) Chapter 50. Bronchopulmonary Dysplasia (Davis, Abman) Section XI. Neurologic Considerations in the Neonate Chapter 51. Retinopathy of Prematurity (Quinn) Chapter 52. Neurologic Examination (Brown) Chapter 53. Perinatal Asphyxia and Hypoxic-Ischemic Brain Injury in the Term Infant (duPlessis) Chapter 54. Intracranial Hemorrhage and Leukomalacia in Preterm Infants (Graziani, Wiswell) Chapter 55. Prenatal Contributions to a Neonatal Brain Disorder (Scher) Chapter 56. Follow-up of the High-Risk Neonate (Bernbaum, Gerdes, Spitzer) Section XII. Cardiovascular Disease In The Neonate Chapter 57. Malformations of the Central Nervous System (Murphy, Halamek, Stevenson) Chapter 58. Cardiovascular Disease in the Neonate (Sullivan, Drummond) Chapter 59. Fetal Echocardiography in the Detection and Management of Fetal Heart Disease (Benoit, Copel) Chapter 60. Medical Management of Congenital Heart Disease (Hsu, Gersony) Chapter 61. Congenital Heart Defects in Newborns and Infants: Cardiothoracic Repair (Russo P, Russo J) Chapter 62. Diagnosis and Management of Cardiac Dysrhythmias (Anisman) Section XIII. Nutrition And Gastrointestinal Tract Of Neonates Chapter 63. Feeding the Critically III Neonate (Peirera, Chan SW) Chapter 64. Intravenous Alimentation (Spear, Coleman) Chapter 65. Congenital Anomalies of the Gastrointestinal Tract (Arthur, Schwartz) Chapter 66. Necrotizing Enterocolitis (Srinivasan, Burdjalov) Section XIV. Liver And Biliary Tree Of The Neonate Chapter 67. Cholestatic Syndromes in Neonates (Tung, Projansky) Chapter 68. Hyperbilirubinemia (Watchko) Section XV. Infection And The Neonate Chapter 69. Viral Infections of the Fetus and Neonate (Nachman) Chapter 70. Diagnosis of Neonatal Sepsis (Polin, Harris) Chapter 71. Prevention and Treatment of Neonatal Sepsis (Harris, Casey) Section XVI. Metabolic And Endocrine Disorders Of The Neonate Chapter 72. Neonatal Thyroid Disorders (Lane, Wilson) Chapter 73. Disorders of the Adrenal Cortex (Ross) Chapter 74. Metabolic Disorders of Glucose and Other Sugars (Katz LL, Stanley) Chapter 75. Disorders of Calcium Homeostasis (Greer) Chapter 76. Inborn Errors of Metabolism Presenting As Catastrophic Disease (Yudkoff, Payan, Ganesh) Chapter 77. Fluid and Electrolyte Physiology (Stephano) Section XVII. Renal Disorders In The Neonate Chapter 78. Neonatal Hypertension and Renovascular Disease (Foreman) Chapter 79. Acute Renal Failure (Adelman, Karlowicz) Chapter 80. Chronic Renal Disease (Kaplan, Kaplan, Meyers) Chapter 81. Renal Tubular Disorders (Kaplan, Kaplan, Meyers) Section XVIII. Hematologic Problems In The Neonate Chapter 82. Anemia (MacKenzie) Chapter 83. Neonatal Thrombosis, Hemostasis and Platelet Disorders (Parker) Chapter 84. White Cell Disorders in the Neonate (Koenig, Yoder) Chapter 85. Transfusion Therapy (Manno, Axum, Friedman) Section XIX. Surgical Management Of The Neonate Chapter 86. Surgical Management of the Neonate (Katz A, Wolfson P) Chapter 87. Urological Abnormalities and Treatment (Figueroa TE, Kennedy) Section XX. Ethical Considerations in Neonates Chapter 88. Neonatal Ethics and Epidemiology at the Dawn of a New Millennium (Meadow W, Frain, Ren, Soneji, Lee G, Lin, Meadow X, Lanton, Plesha-Troyke) Chapter 89. The Care of the Family (Spitzer)