Opening Remarks-Human T-Cell Growth Factor, Growth of Human Neoplastic T Cells, and Human T-Cell Leukemia-Lymphoma Virus.- I-Thymic Hormones.- 1. Thymosins: Isolation, Structural Studies, and Biological Activities.- 2. Thymulin: New Biochemical Aspects.- 3. Use of Monoclonal Antibodies to Identify Antigens of Human Endocrine Thymic Epithelium.- 4. Abnormal Levels of Thymosin ?1 and the Destruction of the Thymus Gland in the Acquired Immune Deficiency Syndrome.- 5. Thymic Epithelial Injury in the Acquired Immune Deficiency Syndrome.- 6. Increased Thymosin Levels Associated with Acquired Immune Deficiency Syndrome.- 7. Thymosin ?4: Distribution and Biosynthesis in Vertebrate Cells and Tissues.- 8. The Finding and Significance of Spermidine and Spermine in Thymic Tissue and Extracts.- 9. Synthetic Small Thymic Peptides: An Immunoregulatory Concept.- 10. Human Peripheral Blood Lymphocytes Bear Markers for Thymosins (?1, ?7, ?4).- 11. Thymosin ?4 Is Present in a Subset of Oligodendrocytes in the Normal Human Brain.- 12. The Synthesis and Physical Properties of Thymosin ?1 and Its Analogs Prepared by Fragment Condensation.- 13. Immonocytochemical Localization of Thymosin and Thymopoietin in Human, Rat, and Murine Thymus.- 14. Thymus- and Spleen-Derived Immunosuppressive Peptides.- 15. Production of a Thymosin ?1-like Material by T-Cell Lymphomas.- 16. Purification and Characterization of an Immunoreactive Thymosin ?1 from Human Blood: Evidence for a Thymosin ?1 Carrier Protein.- I Summary-Thymic Hormones.- II-Lymphokines.- 17. Characterization of Immunoaffinity-Purified Human T-Cell Growth Factor from JURKAT Cells.- 18. The Use of Lymphoid Cells Expanded in IL-2 for the Adoptive Immunotherapy of Murine and Human Tumors.- 19. Biochemical and Biological Properties of Interleukin-3.- 20. Lymphotoxins, a Multicomponent Family of Effector Molecules: Purification of Human ?-Lymphotoxin from a Cloned Continuous Lymphoblastoid Cell Line IR 3.4 to Homogeneity.- 21. Chemical and Biological Properties of Human Lymphotoxin.- 22. T-Cell Growth Factor: Purification, Interaction with a Cellular Receptor, and in Vitro Synthesis.- 23. Demonstration and Characterization of Human Intracellular Interleukin-1.- 24. Silicic Acid Batch Adsorption Procedure for the Partial Purification of Interleukin-2 from Cultures of Primary Lymphocytes and Long-Term T-Cell Lines.- 25. TCGF (IL-2) Receptor (Tac Antigen) on ATL and Non-ATL Leukemic Cells.- II Summary-Chemistry and Biological Activity of Lymphokines.- III-Mechanism of Action and Immune Regulation.- 26. Lymphocyte Proliferation, Lymphokine Production, and Lymphocyte Receptors in Aging.- 27. Augmentation of Antibody Synthesis in Vitro by Thymosin Fraction 5: The Influence of Age.- 28. The Production and Characterization of Monoclonal Antibodies to Lymphokines.- 29. Modulatory Interactions between the Central Nervous System and the Immune System: A Role for Thymosin and Lymphokines.- 30. Effects of Thymic Peptides on Hypothalamic-Pituitary Function.- 31. Biochemistry of Lymphokine Action on Macrophages: Modulation of Macrophage Superoxide Production by Lymphokine.- 32. Modulation of Macrophage Phenotypes by Migration Inhibitory Factors.- 33. The Anticancer Action of Lymphotoxin.- 34. Pituitary Responses to Acute Administration of Thymosin and to Thymectomy in Prepubertal Primates.- 35. Expression of T-Cell Markers on Chicken Bone Marrow Precursor Cells Incubated with an Avian Thymic Hormone.- 36. Transferrin Receptor Induction in Mitogen-Stimulated Human T Lymphocytes Is Required for DNA Synthesis and Cell Division and Is Regulated by Interleukin-2 (TCGF).- III-Chairman's Essay: The Relationship of Terminology to Conceptualization.- IV-Pharmacology and in Vivo Action.- 37. Phase I Trial of Intravenous Lymphokine MAF.- 38. Interaction of Thymic Hormones with Prostaglandins.- 39. A Small-Molecular-Weight Growth Inhibitory Factor (SGIF) in Stationary-Phase Supernatants of Tissue Cultures: A Preliminary Report.- 40. Efficacy of Thymosin ?1 in Animal Models.- 41. The in Vivo Effect of Thymosin on Cell-Mediated Immunity.- 42. Effect of Thymosin ?1 on Immunoregulatory T Lymphocytes.- 43. Treatment of the Diabetic, Autoimmune db/db Mouse with Thymosin.- 44. Role of Thymosin Fraction 5 in Host Defenses to Leukemia in Nutritionally Stressed Mice.- 45. Tumor Growth, Interleukins, and Immune Complexes.- 46. Interleukin-3 Production and Action in Tumor-Bearing Hosts.- 47. Lymphokine-Mediated Enhancement of Antibody Formation by Leukemic Cells.- IV Summary-Pharmacology and in Vivo Actions.- V-Clinical Applications.- 48. A Phase I Trial of Immune Interferon: A Preliminary Report.- 49. The Response of Tumor-Bearing Patients to the Injection of Lymphoid Cell Line Lymphokine.- 50. Clinical Studies of Lymphoid Cell Lymphokines in 102 Patients with Malignant Solid Tumors.- 51. Regulation of T-Cell Proliferation by Interleukin-2 in Male Homosexuals with Acquired Immune Deficiency Syndrome.- 52. Incorporation of Porcine Thymic Peptides into the Treatment of Fulminant Viral Hepatitis.- 53. Use of Porcine Thymic Immunomodulator in the Treatment of Chronic Hepatitis B.- 54. Biological Properties and Clinical Use of Calf Thymus Extract TFX-Polfa.- 55. Role of Thymostimulin (TP-1) as an Immunomodulator in Hodgkin's Disease.- 56. Thymosin Fraction 5 Treatment of Patients with Cellular Immunodeficiency Disorders.- 57. Effect of Thymosin on in Vitro Immune Function in Patients with Rheumatoid Arthritis.- 58. Phase I Trial Using Thymosin Fraction 5 in Renal Cancer: NCOG Report.- 59. Clinical Aspects of Thymulin (FTS).- 60. An Evaluation of Two Different Schedules of Synthetic Thymosin ?1 Administration in Patients with Lung Cancer: Preliminary Results.- 61. Effect of Thymosin Fraction 5 on Purine Enzymes and Surface Markers in Lymphocytes from Normal Individuals and Homosexuals with Acquired Immune Deficiency Syndrome.- 62. Demonstration of a Block at an Early Stage of T-Cell Differentiation in Severe Combined Immunodeficiency Disease.- V Summary-Clinical Applications.- Participants.
