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Antibiotics - Therapeutic Spectrum and Limitations Summary

Antibiotics - Therapeutic Spectrum and Limitations by Amal Kumar Dhara (PhD Department of Pharmacy, Contai Polytechnic, Purba Medinipur, West Bengal, India)

Antibiotics: Therapeutic Spectrum and Limitations provides up-to-date information on managing microbial infections, the development and types of antibiotics, the rationale for utilizing antibiotics, toxicity considerations, and the control of antibiotic resistance in one single resource. This book also aims to provide comprehensive insights and current trends on antibiotic therapies to treat microbial infections, their mechanisms of action, and the role of modern drug delivery in improving their efficacy. Written by leading experts from around the globe, the chapters in the book covers important aspects of microbial infections including hospital acquired infections and community acquired infections and adult sepsis, examines the various types of antibiotics with different mechanisms and therapeutic uses, the global challenge of antibiotic resistance, and clinical trials, regulatory considerations, and market overview of antibiotics. Furthermore, the chapters include updated literature reviews of the relevant key topics, high-quality illustrations, chemical structures, flowcharts, and well-organized tables, all of which enable better understanding by the readers.

About Amal Kumar Dhara (PhD Department of Pharmacy, Contai Polytechnic, Purba Medinipur, West Bengal, India)

Dr. Amal Kumar Dhara (M. Pharm, PhD) has over 20 years of teaching and research experience in the field of Pharmacology and Toxicology, especially in the field of Neuropharmacology, Anti-inflammatory, Antiulcer, free radical scavenging activities of Indian indigenous plants. He has earned his PhD in Pharmaceutical Sciences from Jadavpur University, Kolkata, West Bengal, India. Currently, Dr. Dhara is working as Lecturer in Pharmacy (Selection Grade -II Equivalent to Associate Professor) at Contai Polytechnic, Govt. West Bengal, India. Dr. Dhara has also served as Production Executive at M/S Deys Medical Stores Mfg (UP) Ltd., U.P., India for more than three years. Till date, he has authored over 10 research and review publications in various high impact peer-reviewed journals. Dr. Dhara has participated and presented his research work at several conferences in India and abroad. He is life member of Indian Pharmaceutical Association, Indian Pharmacological Society and a Registered Pharmacist. Dr. Amit Kumar Nayak is currently working as a Professor at Seemanta Institute of Pharmaceutical Sciences, Odisha, India. He earned his Ph.D. in Pharmaceutical Sciences from IFTM University, India. He worked as Senior Research Associate at IIT, Kanpur in a CSIR sponsored project. Dr. Nayak has over 13 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems made of natural biopolymers. He has authored over 130 research and review articles in various high impact peer-reviewed journals and 135 book chapters in various international books. In addition, he has authored 2 books and edited 17 books published by International publisher(s). He has received University Foundation Day Research Award-2019 by Biju Patnaik University of Technology, Odisha. He serves as a reviewer for several reputed journals and is a life member of Association of Pharmaceutical Teachers of India (APTI). Dr Chattopadhyay served as a Scientist at RMRC Port Blair and Dibrugarh during 1993-1996, and ICMR Virus Unit, Kolkata since 1997. He is one of the researchers who extensively studied the scientific basis of use of traditional medicines in primary health care of diverse ethnic communities by establishing personal contact with the underprivileged, marginalised tribal communities of India. His research includes Microbiology, Molecular Medicine and Ethnomedicinal drug development. He has one US and six Indian Patents with three leads (against HSV, Typhoid and Wound Healing) with 100+ Research publications in peer reviewed International and Indian Journals including PLoS Pathogen, Journal of Biological Chemistry, Journal of Antimicrobial Chemotherapy, PLoS One, International Journal of Antimicrobial Agents, Antiviral Research, RSC Advances etc with several reviews like Biotechnology Annual Review, book chapters, three Books, and fifty popular articles. He is in the Editorial Board of 3 International Journals, Reviewer of 37+ International peer reviewed Journals, Examiner, Ph D Guide and visiting Faculty of several International and National Universities and is the recipient of Awards like Outstanding Ethnopharmacologist Award 2016, International Society for Chemotherapy Award, DST Science Communicator Award. He is the Fellow of British Society for Antimicrobial Chemotherapy. Dr Chattopadhyay is the member of National Project review Committees of diverse funding agencies in India, has guided 10 PhD and 40+Master Degree Dissertation of various Universities, competed 9 major National Task Force Projects on Ethnomedicines of Onge, Nicobarese, Shompen, Birhore, Kattabhai, Santal, Munda etc. He is presently handling four National Projects and leading a team of 17 Scholars in collaboration with Internationally acclaimed scientists. He is now leading an Institution that integrate the traditional knowledge with the modern medicine to translate traditional information into innovation.

Table of Contents

Section I: Introduction 1. Introduction to antibiotic therapy Section II: Microbial infection and antibiotics development 2. Bacterial infection: Types and pathophysiology 3. Antibiotics - Past, Present & Possibilities 4. Challenges in the development of antibiotics Section III: Antibiotics and therapeutics 5. Beta lactum antibiotics 6. Aminoglycoside antibiotics 7. Broad Spectrum Antibiotics (Chloramphenicol and Tetracycline) 8. Macrolide antibiotics 9. Lincosamide and glycopeptide antibiotics 10. Antimicrobial Lipopeptides: Multifaceted Designs to Curb Antimicrobial Resistance 11. Antifungal Compounds: With Special Emphasis on Echinocandins, Polyenes, Heterocyclic Benzofurans 12. Antibiotics in the management of tuberculosis and cancer Section IV: Toxicity and Antibiotic resistance 13. Toxicity consideration of antibiotics 14. Rational use of antibiotics- save antibiotics for future generations 15. Combined use of antibiotics 16. Antibiotic resistance - a global crisis 17. Traditional Medicine in the Management of Microbial Infection as Antimicrobials: Pros and Cons Section V: Others 18. Quinolones as antimicrobial and anti-resistance agents 19. Herbal drugs as antibiotics 20. Paediatric and geriatric uses of antibiotics 21. Role of antibiotics in hospital acquired infections and community acquired infections 22. Adult sepsis as an emerging hospital acquired infection: challenges and solutions 23. Probiotics: A solution to the prevention of antimicrobial resistance 24. Role of modern drug delivery in antibiotic therapy 25. Antibiotic residues in food 26. Clinical trials, regulatory considerations and market overview of antibiotics

Additional information

NGR9780323953887
9780323953887
0323953883
Antibiotics - Therapeutic Spectrum and Limitations by Amal Kumar Dhara (PhD Department of Pharmacy, Contai Polytechnic, Purba Medinipur, West Bengal, India)
New
Paperback
Elsevier Science & Technology
2023-07-01
550
N/A
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