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Atherosclerosis Pathogenesis and Microvascular Dysfunction Axel Haverich

Atherosclerosis Pathogenesis and Microvascular Dysfunction By Axel Haverich

Atherosclerosis Pathogenesis and Microvascular Dysfunction by Axel Haverich


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Summary

When seen through this lens, novel preventive and therapeutic opportunities can be envisioned.

Atherosclerosis Pathogenesis and Microvascular Dysfunction proposes a single unifying mechanism of atherosclerosis development and describes potential preventative and therapeutic avenues based on this concept.

Atherosclerosis Pathogenesis and Microvascular Dysfunction Summary

Atherosclerosis Pathogenesis and Microvascular Dysfunction by Axel Haverich

This book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well as for aortic and peripheral artery dissection. When seen through this lens, novel preventive and therapeutic opportunities can be envisioned.

Atherosclerosis Pathogenesis and Microvascular Dysfunction proposes a single unifying mechanism of atherosclerosis development and describes potential preventative and therapeutic avenues based on this concept. It therefore represents a timely and valuable resource for internal medicine, cardiology, angiology cardiovascular surgeons, pathology clinicians, researchers, trainees, and students.

About Axel Haverich

Professor Axel Haverich completed his medical training at the MHH and was appointed head of Cardiovascular Surgery at the University of Kiel in 1993. Since 1996, he has been the head of the Department of Cardiothoracic, Transplantation and Vascular Surgery at MHH. In 1995, he won the prestigious Leibniz Prize from the German Research Foundation (DFG). With this award, he founded the Leibniz Research Laboratories for Biotechnology and Artificial Organs. There, the foundation was laid for many scientific achievements including bioengineered heart valves that grow with the patient and a bioengineered vascular graft for coronary reconstruction based on an autologous fibrin matrix. His company CorLife has provided >250 decellularized heart valves to children and adolescents. Here, two clinical trials have been funded by EU grants. He has been granted several patents in the field of tissue engineering, such as for a biological vascularized autologous matrix which can replacedamaged myocardium. Prof. Haverich served as the coordinator of the Excellence Cluster From Regenerative Biology to Reconstructive Therapy from 2006 to 2018. In addition to being the Chairman of the German Society for Thoracic and Cardiovascular Surgery from 2007-2009, he was the president of the German Society of Surgery from 2010 to 2011. He has published over 1000 peer-reviewed papers and has contributed to numerous books.
Dr. Erin Colleen Boyle received her Bachelor of Science (Specialized Honors, Microbiology) from the University of Guelph and her PhD from the Department of Microbiology and Immunology at the University of British Columbia. She was awarded an Alexander von Humboldt Postdoctoral Research Fellowship in 2010. In 2015, Dr. Boyle joined the Department of Cardiothoracic, Transplantation and Vascular Surgery at Hannover Medical School (MHH). She has published numerous primary research and review papers in high-level peer-reviewed journals on the topics of bacterial pathogenesis and atherosclerosis.

Table of Contents

Introduction.-Atherosclerosis Risk Factors.-The Effect Of Growth And Aging On Vascular Architecture.-Incriminating Evidence For The Role Of The Microvasculature In Atherosclerosis.-Risk Factors And Prevention In Light Of Atherosclerosis Being A Microvascular Disease.-New Ways To Target Vasa Vasorum For The Prevention And Treatment Of Atherosclerosis.-Outstanding Questions and Future Directions.

Additional information

GOR013928114
9783030202446
3030202445
Atherosclerosis Pathogenesis and Microvascular Dysfunction by Axel Haverich
Used - Very Good
Hardback
Springer Nature Switzerland AG
2019-08-08
130
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a used book - there is no escaping the fact it has been read by someone else and it will show signs of wear and previous use. Overall we expect it to be in very good condition, but if you are not entirely satisfied please get in touch with us

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