Name: Psychotic Disorders By Carol A. Tamminga (Chairman, Department of Psychiatry Professor of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia, Chairman, Department of Psychiatry Professor of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia, University of Texas Southwestern Medical Center)
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Psychotic Disorders Summary

Psychotic Disorders: Comprehensive Conceptualization and Treatments by Carol A. Tamminga (Chairman, Department of Psychiatry Professor of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia, Chairman, Department of Psychiatry Professor of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia, University of Texas Southwestern Medical Center)

Psychotic Disorders: Comprehensive Conceptualization and Treatments emphasizes a dimensional approach to psychosis--one of the most fascinating manifestations of altered brain behavior--that cuts across a broad array of psychiatric diagnoses from schizophrenia to affective psychosis and organic disorders like epilepsy and dementias. Written by an international roster of over seventy leading experts in the field, this volume comprehensively reviews, critiques, and integrates available knowledge on the etiology, mechanisms, and treatments of psychotic disorders, and outlines ways forward in both research and clinical practice towards more objective, mechanistically-based definitions of psychotic disorders. Chapters address topics such as psychosis phenomenology, biomarkers and treatments, the overlaps and interfaces between psychiatric disorders within the psychosis dimension, and novel disease definitions. Furthermore, the volume incorporates findings on potential mechanisms, bridges between various system levels (i.e., genetic, epigenetic, molecular and cellular, brain circuit and function, psychological, social, environmental and cultural) and their interactions, as well as the potential role in causation and/or mediation in psychotic disorders. Finally, the volume outlines a broad array of treatment approaches, from the readily available (e.g., psychopharmacology, various modalities of psychotherapy) to the experimental (e.g., cognitive interventions, neuromodulation). With a concluding section of forward perspectives conjecturing future directions and related challenges, this book aspires to stimulate new knowledge, generate novel frameworks, and carry new directions forward on psychotic disorders.

About Carol A. Tamminga (Chairman, Department of Psychiatry Professor of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia, Chairman, Department of Psychiatry Professor of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia, University of Texas Southwestern Medical Center)

Carol A. Tamminga, MD is Professor, Chairman of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia at the University of Texas Southwestern Medical School. She holds the Communities Foundation of Texas Chair in Brain Science along with the Lou and Ellen McGinley Distinguished Chair in Psychiatric Research. She directs clinical and preclinical research in schizophrenia focused on identifying disease mechanisms and on improving treatments. Dr. Tamminga has been the recipient of numerous federal and foundation grants, as well as Award in the field. She has served on the National Advisory Mental Health Council, NIMH and the Council of the National Institute of Drug Abuse. The goal of Dr. Tamminga's research is to examine and understand the mechanisms underlying schizophrenia, especially its most prominent symptoms, psychosis and memory dysfunction, in order to build rational treatments for the illness. Elena I. Ivleva, MD, PhD is a psychiatrist and neuroscientist specializing in psychotic disorders. Dr. Ivleva completed her medical training, psychiatry residency and PhD in Neuroscience at the Voronezh State Medical Academy, Russia. She subsequently completed postdoctoral research fellowship in translational schizophrenia research, as well as psychiatry residency, at UT Southwestern Medical Center, Dallas. Since 2012, Dr. Ivleva has been a faculty member at the Department of Psychiatry at UT Southwestern Medical Center. She is also a director of clinical and research Early Psychosis Program at UT Southwestern. Dr. Ivleva's research is focused on understanding neurobiological mechanisms of psychosis, and developing brain-based biomarkers for psychotic illness. The ultimate goal of her research is to develop objective, measurable biomarkers which could inform future diagnostic algorithms and mechanism-based treatments for psychotic disorders. Ulrich Reininghaus, PhD, is Heisenberg Professor at the Department of Public Mental Health, Central Institute of Mental Health (CIMH), Mannheim, and a Visiting Professor at the Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London. Professor Reininghaus has been awarded several competitive fellowships and personal grants for his work, including a Research Training Fellowship by the UK National Institute for Health Research (NIHR), an NIHR Postdoctoral Fellowship, a Veni grant by the Netherlands Organisation for Scientific Research (NWO), a ZonMw research programme grant, and most recently a Heisenberg Professorship by the German Research Foundation to establish the new Department of Public Mental Health at CIMH. He is also Associate Editor and commissions the state-of-the-art review series of the international peer-reviewed journal Social Psychiatry and Psychiatric Epidemiology. Jim van Os MD, PhD, is Professor of Psychiatric Epidemiology and Chairman of the Division Neuroscience at Utrecht University Medical Centre, Utrecht, The Netherlands, and Visiting Professor of Psychiatric Epidemiology at the Institute of Psychiatry, London. He is on the editorial board of numerous European and US psychiatric journals and an Academic Editor at PLoS ONE. In 2011, he was elected member of the Royal Netherlands Academy of Arts and Sciences (KNAW); in 2016 he became a Fellow at King's College London; and since 2014, he has appeared on the Thomson-Reuter Web of Science list of the worlds' "most influential scientific minds' of our time. He leads the Division Neuroscience at Utrecht University Medical Centre and is actively involved in mental health reform in the Netherlands as well as Science in Transition, a movement that works towards making scientific research more relevant and impactful.

Section 1: Phenomenological characteristics and dimensional conceptualization of psychosis 1. Conceptualization of psychosis in psychiatric nosology: past, present and the future Matcheri S. Keshavan, John Torous, Rajiv Tandon 2. Historical epistemology of the "unitary psychosis" German E. Berrios, Ivana S. Markova 3. Dimensional conceptualization of psychosis Kursat Altinbas, Sinan Guloksuz, and Jim van Os Transdiagnostic dimensions of psychosis 4. Applying Research Domain Criteria (RDoC) Dimensions to psychosis Sarah E. Morris, Jennifer Pacheco, Charles A. Sanislow 5. Schizophrenia, Schizoaffective disorder, Bipolar Disorder Barrett Kern, Sarah K. Keedy 6. Psychotic symptoms in bipolar disorder Marsal Sanches, Xiang-Yang Zhang, and Jair C. Soares 7. Major depressive disorder with psychotic features: confronting and resolving the dimensional challenge John L. Waddington, Tara Kingston, Nnamdi Nkire, Vincent Russell 8. Psychosis in Personality Disorders Nidhi Kapil-Pair, Yulia Landa, Marie C. Hansen, Daniel H. Vaccaro, Marianne Goodman 9. Symptom network models of psychosis Adela-Maria Isvoranu, Lindy-Lou Boyette, Sinan Guloksuz, Denny Borsboom Psychosis in general medical conditions and organic brain disorders 10. Organic psychosis: phenotypic deviants or clues to schizophrenia? Peter Buckley, Brian Miller 11. Epilepsy and psychosis Michael R. Trimble, Kousuke Kanemoto, Dale C. Hesdorffer 12. Understanding sex differences in psychosis through the exploration of hormonal contributions Leah H. Rubin Section 2: Psychosis course and lifetime manifestations Early Psychosis 13. Clinical phenomenology of the prodrome for psychosis Albert R. Powers III, Thomas H. McGlashan, Scott W. Woods 14. Predictors of conversion to psychosis Rachael G. Grazioplene, Tyrone D. Cannon 15. First-episode psychosis: phenomenology, onset, course and early intervention (OPUS) Merete Nordentoft, Nikolai Albert 16. Evidence based treatment and implementation for early psychosis Sacha Zilkha, Iruma Bello, Hong Ngo, Samantha Jankowski, Lisa Dixon Psychosis Over Life Span and Late-Life Psychosis 17. Life span development of schizophrenia: symptoms, clinical course and outcomes Matt Isohanni, Jouko Miettunen, Matti Penttila 18. Phenomenological characteristics of psychosis of aging: psychosis and dementia interphase Graham M.L. Eglit, Barton W. Palmer, Dilip V. Jeste Section 3: Neurobiology of psychosis Heritability and Genetics 19. Genetic neuropathology revisited: gene expression in psychosis Samuel J. Allen; Rahul Bharadwaj,, Thomas M. Hyde, Joel E. Kleinman 20. Epigenomic regulation in psychosis Bibi S. Kassim, Behnam Javidfar, Schahram Akbarian 21. DNA modifications in schizophrenia Ehsan Pishva, Bart P. F. Rutten, Jonathan Mill 22. Endophenotypes: a window on the genetics of schizophrenia David Braff Cognitive Biomarkers of psychosis 23. Cognitive biomarkers of psychosis S. Kristian Hill, Richard S.E. Keefe, John A. Sweeney 24. Social cognition in psychosis Amy E. Pinkham, David L. Roberts 25. Self-awareness in schizophrenia: affected domains and their impact Juliet M. Silberstein, Amy E. Pinkham, Philip D. Harvey Neurophysiologic biomarkers of psychosis 26. Neurophysiologic biomarkers of psychosis: Event-related potential biomarkers Judith M. Ford, Holly K. Hamilton, Katiah Llerena, Brian J. Roach, Daniel H. Mathalon 27. Oculomotor biomarkers of illness, risk, and pharmacogenetic treatment effects across the psychosis spectrum James L Reilly, Jennifer McDowell, Jeffrey Bishop, Andreas Sprenger, Rebekka Lencer Brain imaging biomarkers 28. Structural connectivity in psychosis Amanda E. Lyall, Johanna Seitz, Marek Kubicki 29. Functional connectivity biomarkers of psychosis Godfrey Pearlson, Michael Stevens 30. MR Spectroscopy Adrienne C. Lahti, Nina V. Kraguljac Pathophysiology of Psychosis: Neurotransmitters 31. Dopaminergic mechanisms underlying psychosis Oliver Howes & Michael Bloomfield 32. Glutamate in the pathophysiology of schizophrenia Daniel C. Javitt 33. GABAergic Mechanisms in Psychosis Takanori Hashimoto, David A Lewis 34. Alteration in nicotinic receptors in psychotic disorders: molecular neurobiology and clinical relevance Robert Freedman 35. Muscarinic acetylcholine receptors in the etiology and treatment of schizophrenia M.S. Moehle, S. E. Yohn, and P. J. Conn 36. Kynurenic acid in brain function and dysfunction: focus on the pathophysiology and treatment of schizophrenia Robert Schwarcz and Sophie Erhardt Pathophysiology: Voltage-gated ion channels in psychosis 37. Genetic Association of Voltage-gated Ion Channels with Psychotic Disorders Charles H Large 38. Voltage-gated Ion channels in neural circuits implicated in psychotic disorders Charles H Large Pathophysiology: Immune Mechanisms 39. Inflammatory mechanisms in psychosis Anna P. McLaughlin, Carmine M. Pariante, Valeria Mondelli 40. Autoimmune processes in mental disorders Marina Mane-Damas, Carolin Hoffmann, Shenghua Zong, Peter C. Molenaar, Mario Losen, Pilar Martinez-Martinez Brain circuit alterations in psychosis 41. The circuitry of midbrain dopamine system dysregulation in schizophrenia Felipe V. Gomes, Eric C. Zimmerman, Anthony A. Grace 42. Feeling and remembering: effects of psychosis on the structure and function of the amygdala and hippocampus M.D. Bauman, J.D. Ragland, C.M. Schumann 43. The cerebellum in psychosis Kelsey Heslin, Joe Shaffer, Albert Powers, Nancy Andreasen, and Krystal Parker Section 4: Socio-environmental mechanistic factors in psychosis Early life adversity 44. Perinatal factors in psychosis Mary Clarke, Mary Cannon 45. The role of early life experience in psychosis Richard P. Bentall 46. Socio-environmental adversity across the life span Peter Bosanac, David Castle 47. Migration, ethnicity, and psychoses Craig Morgan Psychological mechanisms and psychosis 48. Cognitive and emotional processes in psychosis Steffen Moritz, Thies Ludtke, Lukasz Gaweda, Jakob Scheunemann, and Ryan P. Balzan 49. Aberrant salience attribution and psychosis Toby T. Winton- Brown and Shitij Kapur Neural correlates of socio-environmental risk and psychosis 50. Neural correlates of childhood trauma Alaptagin Khan, Kyoko Ohashi, Maria Maierd, Martin H. Teicher 51. Neural correlates of urban risk environments Imke L.J. Lemmers-Jansen, Anne-Kathrin J. Fett, Lydia Krabbendam 52. Neural correlates of ethnic minority position and risk for psychosis Jean-Paul Selten, Jan Booij, Bauke Buwalda, Andreas Meyer-Lindenberg 53. Resilience in psychosis spectrum disorder Lotta-Katrin Pries, Sinan Guloksuz, Bart P. F. Rutten Section 5: Treatment of psychotic disorders Pharmacological Treatments 54. Pharmacological approaches to treatment Stefan Leucht, Andrea Cipriani, Toshi A. Furukawa 55. Animal models of psychosis: approaches and validity Daniel Scott Psychological treatments in psychosis 56. Psychoanalytic treatment of psychosis Elyn R. Saks 57. Cognitive-behavioral therapy Tania Lincoln, Alison Brabban 58. Psychoeducation as an approach to treatment of severe mental illness Emma Sophia Kay, David E. Pollio, Carol S. North 59. Family Interventions in psychosis Juliana Onwumere, Elizabeth Kuipers 60. Peer support for people with psychiatric illness: A comprehensive review Chyrell D. Bellamy, Anne S. Klee, Xavier Cornejo, Kimberly Guy, Mark Costa, Larry Davidson 61. Mind-body approaches, mindfulness Louise Johns, Mark Hayward, Clara Strauss, Eric Morris 62. Hearing voices groups Alison Branitsky, Eleanor Longden and Dirk Corstens 63. AVATAR Therapy: a new digital therapy for Auditory Verbal Hallucinations Tom K.J. Craig, Mar Rus-Calafell 64. Health in a connected world Philippe Delespaul and Catherine van Zelst 65. Recovery-oriented services Mike Slade, Eleanor Longden, Julie Repper, Samson Tse Cognitive Remediation and Other Approaches 66. Neuroscience-informed cognitive training for psychotic spectrum illnesses Sophia Vinogradov, Rana Elmaghraby, Laura Pientka 67. Cognitive remediation: theory, meta-analytic evidence, and practice Til Wykes and Adam Crowther 68. Noninvasive brain stimulation techniques in psychosis Marine Mondino, Frederic Haesebaert, Jerome Brunelin Early interventions 69. Treatment approaches in the psychosis prodrome Andrea M. Auther and Barbara A. Cornblatt 70. From early intervention in psychosis to transformation of youth mental health reform Ashok Malla, Patrick McGorry Section 6: Future directions and opportunities 71. Future directions: making a start towards the primary prevention of psychosis Robin M Murray, Olesya Ajnakina and Marta Di Forti 72. A glimpse forward regarding psychopathology of psychotic disorders William T. Carpenter 73. Time for change in psychosis research Brett A. Clementz

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NPB9780190653279

ISBN 13

9780190653279

ISBN 10

0190653272

Title

Psychotic Disorders: Comprehensive Conceptualization and Treatments by Carol A. Tamminga (Chairman, Department of Psychiatry Professor of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia, Chairman, Department of Psychiatry Professor of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia, University of Texas Southwestern Medical Center)

Author

Carol A. Tamminga (Chairman, Department of Psychiatry Professor of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia, Chairman, Department of Psychiatry Professor of Psychiatry and Chief of Translational Neuroscience Research in Schizophrenia, University of Texas Southwestern Medical Center)

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Hardback

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Oxford University Press Inc

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2021-01-19

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708

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Psychotic Disorders Summary

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