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Drug Design and Development Summary

Drug Design and Development by Chris Rostron (Honorary Research Fellow in the School of Pharmacy and Biomolecular Sciences at Liverpool John Moores University, Honorary Research Fellow in the School of Pharmacy and Biomolecular Sciences at Liverpool John Moores University, Chairman of the Academic Pharmacy Forum and Deputy Chair of the Educational Expert Advisory Panel, Royal Pharmaceutical Society)

Drug Design and Development outlines the processes involved in the design and development of new drugs and emphasises the significance of these processes to the practice of pharmacy. The book highlights why it is important that all practicing pharmacists, including those working in hospitals or high street stores, have a solid understanding of the process of the design and development of the drugs they interact with. It adopts an integrated approach, formulated to complement courses which are designed in line with the General Pharmaceutical Council's new curriculum requirements. Furthermore, this is the only integrated textbook to consider both drug design and development within one volume. Throughout the book, the journey of the drug, from discovery to market, is presented in an integrated fashion, emphasising the interconnection of all the processes involved.

Drug Design and Development Reviews

Well written text that guides students through the complex elements of the drug development process. It has a chemistry focus and utilises 'key points' to reinforce the important aspects at regular opportunities. * Dr James F. Brown, University of Portsmouth *

About Chris Rostron (Honorary Research Fellow in the School of Pharmacy and Biomolecular Sciences at Liverpool John Moores University, Honorary Research Fellow in the School of Pharmacy and Biomolecular Sciences at Liverpool John Moores University, Chairman of the Academic Pharmacy Forum and Deputy Chair of the Educational Expert Advisory Panel, Royal Pharmaceutical Society)

Dr Chris Rostron graduated in Pharmacy from Manchester University and completed a PhD in Medicinal Chemistry at Aston University. He gained Chartered Chemist status in 1975. After a period of post-doctoral research he was appointed as a lecturer in Medicinal Chemistry at Liverpool Polytechnic. He is now an Honorary Research Fellow in the School of Pharmacy and Biomolecular Sciences at Liverpool John Moores University. He was a member of the Academic Pharmacy Group Committee of the Royal Pharmaceutical Society of Great Britain and chairman for the past 5 years. He is currently chairman of the Academic Pharmacy Forum and deputy chair of the Education Expert Advisory Panel of the Royal Pharmaceutical Society. He is an external examiner in Medicinal Chemistry at a number of Schools of Pharmacy both in the UK and abroad. In 2008 he was awarded honorary membership of the Royal Pharmaceutical Society of Great Britain for services to Pharmacy education.

Table of Contents

1: Introduction Part 1 Drug targets 2: Receptors and signal transduction 3: Enzymes as drug targets 4: Nucleic acids and protein synthesis as drug targets 5: Other drug targets Part 2 Origins of drug molecules 6: Sources of lead compounds 7: Drug synthesis 8: Optimisation of lead compounds 9: Computer-aided drug design 10: Combinatorial chemistry and high-throughput screening 11: Biotechnology and biopharmaceuticals Part 3 Biological aspects of drug development 12: Drug metabolism 13: Pharmacogenetics and pharmacogenomics 14: Toxicity testing Part 4 Preformulation studies 15: Solubility and drug development 16: Solid state characteristics 17: Drug stability Part 5 Clinical research 18: Clinical research and its regulation 19: Design and management of clinical trials

Additional information

NGR9780198749318
9780198749318
0198749317
Drug Design and Development by Chris Rostron (Honorary Research Fellow in the School of Pharmacy and Biomolecular Sciences at Liverpool John Moores University, Honorary Research Fellow in the School of Pharmacy and Biomolecular Sciences at Liverpool John Moores University, Chairman of the Academic Pharmacy Forum and Deputy Chair of the Educational Expert Advisory Panel, Royal Pharmaceutical Society)
New
Paperback
Oxford University Press
2020-08-20
376
N/A
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