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Homeostatic Control of Brain Function Detlev Boison (PhD, PhD, Legacy Research Institute)

Homeostatic Control of Brain Function By Detlev Boison (PhD, PhD, Legacy Research Institute)

Homeostatic Control of Brain Function by Detlev Boison (PhD, PhD, Legacy Research Institute)


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Summary

Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders.

Homeostatic Control of Brain Function Summary

Homeostatic Control of Brain Function by Detlev Boison (PhD, PhD, Legacy Research Institute)

Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. Incorporation of homeostatic therapies into existing basic and clinical research paradigms. Extensive scientific basic and clinical research ranging from molecules to disorders. Emerging practical information for improving homeostasis. Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.

Homeostatic Control of Brain Function Reviews

Homeostatic Control of Brain Function is a serious resource for scientists at all levels. While outlining detailed mechanisms several dozen experts in the field consider how basic principles of homeostasis influence brain function from molecules to behavior. Accordingly, Homeostatic Control of Brain Function offers insights into why and how to restore homeostasis therapeutically, and perhaps non-pharmacologically. One of the most interesting aspects is up-to-date scientific information underling beneficial and available therapies such as meditation and acupuncture. In sum, Boison and Masino have organized a provocative and forward-looking book as we continue to grapple with new insights and develop therapies for complex and overlapping brain diseases. * Paul Lombroso, MD, Professor and Deputy Chair of Research, Child Study Center and Departments of Psychiatry and Neurobiology, Yale University School of Medicine *

About Detlev Boison (PhD, PhD, Legacy Research Institute)

Detlev Boison is the Robert Stone Dow Chair of Neurology; the Director of Neurobiology Research; and the Director of Basic and Translational Research at the Legacy Research Institute Susan A. Masino is the Vernon Roosa Professor of Applied Science; and a Professor of Neuroscience and Psychology at Trinity College

Table of Contents

Prologue Part I: Homeostatic Regulators: Molecules and Ions Chapter 1: Microdynamics of water and ion homeostasis in the brain: role of aquaporins and ion channels of astroglial cells Chapter 2: Homeostatic control of adenosine levels and functions in brain Chapter 3: Glutamate homeostasis as a regulatory of neurotransmitter recycling and synaptic function) Chapter 4: Homeostasis of neuronal excitability via synaptic and intrinsic inhibitory mechanisms Part II: Homeostatic Control: Systems, Cells and Organelles Chapter 5: Role of astrocytes in sleep and epilepsy Chapter 6: Neuron-astrocyte interactions Chapter 7: Homeostatic synaptic scaling at central synapses Chapter 8: Homeostatic role of heterosynaptic plasticity Chapter 9: The Blood Brain Barrier Chapter 10: Inflammation and immunomodulation in epilepsy and its comorbidities Chapter 11: Neuroplasticity Chapter 12: Epigenetics Chapter 13: Adult neural stem cells and brain homeostasis Part III: Homeostatic Manipulators: Preventative and Restorative Opportunities Chapter 14: Systems (network) pharmacology for brain functionality restoration Chapter 15: Ketogenic diets, mitochondria, and neurological diseases Chapter 16: Dietary manipulations Chapter 17: Exercise Chapter 18: Sleep Chapter 19: Botanicals Chapter 20: The role of acupuncture in nociception homeostasis Chapter 21: Meditation Chapter 22: Neurotrophic regulation in neurorestoration of brain Part IV: Homeostatic Therapies for Disease and Dysfunction Chapter 23: Epilepsy Chapter 24: Traumatic Brain Injury Chapter 25: Adenosine and Alzheimer's Disease, a possible epigenetic link Chapter 26: Brain homeostasis and Parkinson's Disease Chapter 27: Brain homeostasis and addiction Chapter 28: Anxiety and stress disorders Chapter 29: Malignant brain cancer management with metabolic therapy Chapter 30: Obesity and diabetes: Nature, nurture, and beyond Chapter 31: Autism spectrum disorders and homeostasis

Additional information

NPB9780199322299
9780199322299
0199322295
Homeostatic Control of Brain Function by Detlev Boison (PhD, PhD, Legacy Research Institute)
New
Hardback
Oxford University Press Inc
2016-01-21
656
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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