Cart
Free US shipping over $10
Proud to be B-Corp

The Human Hypothalamus Summary

The Human Hypothalamus: Anterior Region: Volume 179 by Dick F. Swaab (Netherlands Institute for Brain Research, University of Amsterdam, Amsterdam, The Netherlands)

The Hypothalamus is an important area of the brain for understanding a variety of neurological disorders. This volume summarizes for readers the anatomy and physiology of the anterior hypothalamus, to better understand pathology and treatment of hypothalamus related disorders. In addition to anatomy and physiology in humans, cytoarchitecture and chemoarchitecture in rodents is provided. The volume explores the role of the hypothalamus in disorders of eating, sleeping, anxiety, and mood, as well as its role in sexual behavior and gender identity. Coverage includes how Parkinson's, Alzheimer's and other neurological disorders relate to the hypothalamus.

About Dick F. Swaab (Netherlands Institute for Brain Research, University of Amsterdam, Amsterdam, The Netherlands)

Dick Swaab (1944) earned his medical and doctoral degrees at the University of Amsterdam, where he became involved in brain research during his third year of medical school. He was Director of the Netherlands Institute for Brain Research from 1978 to 2005. Since 1979 he is Professor of Neurobiology at the Medical Faculty, University of Amsterdam. In 1985, Dr. Swaab founded the Netherlands Brain Bank (NBB) to serve as a source of clinically and neuropathologically well-documented research tissue. Since its founding, the Brain Bank has provided samples from more than 4,000 autopsies to 500 research groups in 25 countries. He was director of the NBB until 2005. He is Leader Research team Neuropsychiatric Disorders, Neth. Inst for Neuroscience, an institute of the Royal Netherlands Academy of Arts and Sciences (KNAW). Swaab is also appointed for 2011-2017 Chao Kuang Piu Chair of Zhejiang University, Hangzhou, P.R. China. His major research interests focus on, sexual differentiation of the human brain in relation to gender identity and sexual orientation, aging of the brain, Alzheimer's disease, the neurobiological basis of depression, suicide and eating disorders. He has published over 540 papers in SCI journals, authored more than 200 chapters in books, and edited more than 60 books. Swaab mentored 84 PhD students from which 16 are now full professor. He is Companion in the Order of the Dutch Lion, bestowed by her Royal Majesty Queen Beatrix of the Netherlands. In 2008 Swaab obtained the Academy medal for his role in national and international neuroscience. Dick Swaab is author of the 2 volume monograph The Human Hypothalamus that appeared in the Handbook of Clinical Neurology series, Elsevier, Amsterdam (1000 pp) and the Dutch best seller We are our Brains (450.000 copies sold), that is translated in 14 languages. A children's version of the book (You are your brains) has also appeared in Dutch in 2013 and Russian (2014). Swaab's H-factor is 76. Felix Kreier is a pediatrician and affiliated with OLVG Hospitals in Amsterdam, The Netherlands. Paul J. Lucassen did his PhD in 1995 on Alzheimer's Disease at the Netherlands Institute for Brain Research in Amsterdam. After a.o. a postdoc in Leiden, he became Full Professor of Brain Plasticity in 2011 at the Swammerdam Institute for Life Sciences (SILS) of the University of Amsterdam, The Netherlands. His group studies molecular, nutritional, pharmacological and environmental regulation of brain plasticity. They combine molecular tools, in vitro/vivo model systems, human brain tissue, cohort studies and brain imaging. A major focus is on adult neurogenesis and cognition in relation to; (early life) stress, exercise, enrichment, depression, brain insults and dementia. Ahmad Salehi is affiliated with Stanford Medical School, Department of Psychiatry & Behavioral Sciences, in Palo Alto, CA, United States. Dr. Ruud M. Buijs is head of the Physiology department of the I.I.Biomedicas at the UNAM university and leader of the group Hypothalamic Integration Mechanisms. In that group, the scientists study how the brain and body interact with each other, and hereby the attention is focussed on autonomic and hormonal regulation of body functions under the influence of the biological clock of the brain.

Table of Contents

SECTION 1 Introduction 1. Introduction: The anterior hypothalamus 2. History of hypothalamic research: The spring of primitive existence 3. Anatomy and cytoarchitectonics of the human hypothalamus 4. Morphology and distribution of hypothalamic peptidergic systems 5. MRI maps, segregation, and white matter connectivity of the human hypothalamus in health 6. Magnetic resonance imaging of the hypothalamo-pituitary region 7. Resting-state functional connectivity of the human hypothalamus 8. Neurogenesis in the adult hypothalamus: A distinct form of structural plasticity involved in metabolic and circadian regulation, with potential relevance for human pathophysiology 9. Matching of the postmortem hypothalamus from patients and controls SECTION 2 The basal forebrain cholinergic system 10. Spatial topography of the basal forebrain cholinergic projections: Organization and vulnerability to degeneration 11. The diagonal band of Broca in health and disease 12. Nucleus basalis of Meynert degeneration predicts cognitive impairment in Parkinson's disease 13. Enlargement of early endosomes and traffic jam in basal forebrain cholinergic neurons in Alzheimer's disease 14. Gene and cell therapy for the nucleus basalis of Meynert with NGF in Alzheimer's disease SECTION 3 The circadian system 15. The circadian system: From clocks to physiology 16. Development of the circadian system and relevance of periodic signals for neonatal development 17. Disrupted circadian rhythms and mental health 18. Diurnal and seasonal molecular rhythms in the human brain and their relation to Alzheimer disease 19. Circadian changes in Alzheimer's disease: Neurobiology, clinical problems, and therapeutic opportunities 20. The circadian system in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy 21. Retina and melanopsin neurons 22. Melatonin and the circadian system: Keys for health with a focus on sleep 23. Melatonin receptors, brain functions, and therapies 24. Chronotherapy 25. The use of melatonin to mitigate the adverse metabolic side effects of antipsychotics SECTION 4 Bed nucleus of the stria terminalis and the fear circuit 26. Chemoarchitecture of the bed nucleus of the stria terminalis: Neurophenotypic diversity and function 27. Functional anatomy of the bed nucleus of the stria terminalis-hypothalamus neural circuitry: Implications for valence surveillance, addiction, feeding, and social behaviors 28. Roles of the bed nucleus of the stria terminalis and amygdala in fear reactions SECTION 5 Preoptic area 29. The median preoptic nucleus: A major regulator of fluid, temperature, sleep, and cardiovascular homeostasis 30. The neuroendocrinology of the preoptic area in menopause: Symptoms and therapeutic strategies 31. The intermediate nucleus in humans: Cytoarchitecture, chemoarchitecture, and relation to sleep, sex, and Alzheimer disease

Additional information

NPB9780128199756
9780128199756
012819975X
The Human Hypothalamus: Anterior Region: Volume 179 by Dick F. Swaab (Netherlands Institute for Brain Research, University of Amsterdam, Amsterdam, The Netherlands)
New
Hardback
Elsevier Science Publishing Co Inc
2021-09-01
542
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a new book - be the first to read this copy. With untouched pages and a perfect binding, your brand new copy is ready to be opened for the first time

Customer Reviews - The Human Hypothalamus