Cart
Free US shipping over $10
Proud to be B-Corp

Protein Formulation and Delivery Eugene McNally (Executive Director, PPD Consulting,)

Protein Formulation and Delivery By Eugene McNally (Executive Director, PPD Consulting,)

Protein Formulation and Delivery by Eugene McNally (Executive Director, PPD Consulting,)


$71.94
Condition - Very Good
Only 1 left

Summary

Provides insight into the approach used to identify the stability profile of a molecule that comes at the end of the drug registration process. This book supplies an review of the mechanisms and associated causes of protein instability. It is for biotechnologists; drug regulatory affairs personnel; and others.

Faster Shipping

Get this product faster from our US warehouse

Protein Formulation and Delivery Summary

Protein Formulation and Delivery by Eugene McNally (Executive Director, PPD Consulting,)

This handy reference provides insight into the approach used to identify the stability profile of a molecule that comes at the end of the drug registration process, and supplies an in-depth review of the mechanisms and associated causes of protein instability likely to be encountered during drug formulation development.
Emphasizes the importance of selecting formulation conditions, excipients, and container closure systems to minimize degradation processes and maximize shelf stability!
Organized to direct scientists new to the field of protein formulation to appropriate starting points of drug development, Protein Formulation and Delivery
  • includes a discussion of accelerated stability testing and its limitations in identifying stable formulations
  • details analytical methods commonly used in stability assessment and formulation development
  • stresses the importance of demonstrating the stability-indicating nature of an assay
  • describes the drug substance manufacturing process succinctly
  • examines preformulation and development of traditional solution and lyophilized formulations intended for intravenous administration
  • covers aseptic processing in drug development and the potential development of a freeze-drying cycle
  • explores the development of nontraditional formulations, alternate routes of drug delivery, and controlled release dosage forms
  • discusses the physical and chemical characteristics of proteins in microsphere delivery systems
  • analyzes protein degradation mechanisms, and methods of detecting and monitoring degradation
  • explores formulations intended for injection, inhalation, and controlled delivery
  • and more!
    Presenting over 660 references and an extensive literature review valuable to scientists at every level, Protein Formulation and Delivery is an indispensable guide for industrial, research, and clinical pharmaceutical scientists, pharmacists, and pharmacologists; drug regulatory affairs personnel; biotechnologists; formulation, analytical, and synthetic chemists and engineers; and upper-level undergraduate and graduate students in these disciplines.
  • Table of Contents

    Overview of Protein Formulation and Delivery
    James Wright
    Chemical and Physical Considerations in Protein and Peptide Stability
    Paul M. Bummer and Sandy Koppenol
    Analytical Methods and Stability Testing of Biopharmaceuticals
    Helmut Hoffmann
    The Importance of a Thorough Preformulation Study
    Eugene J. McNally and Christopher E. Lockwood
    Solution Formulation of Proteins/Peptides
    Paul McGoff and David S. Scher
    Freeze-Drying Concepts: The Basics
    Michael L. Cappola
    Formulation of Proteins for Pulmonary Delivery
    Andrew R. Clark and Steven J. Shire
    Formulation of Proteins for Incorporation into Drug Delivery Systems
    OluFunmi L. Johnson

    Additional information

    CIN0824778839VG
    9780824778835
    0824778839
    Protein Formulation and Delivery by Eugene McNally (Executive Director, PPD Consulting,)
    Used - Very Good
    Hardback
    Taylor & Francis Inc
    19990901
    278
    N/A
    Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
    This is a used book - there is no escaping the fact it has been read by someone else and it will show signs of wear and previous use. Overall we expect it to be in very good condition, but if you are not entirely satisfied please get in touch with us

    Customer Reviews - Protein Formulation and Delivery