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In Vitro Neurotoxicology Evelyn Tiffany-Castiglioni

In Vitro Neurotoxicology By Evelyn Tiffany-Castiglioni

In Vitro Neurotoxicology by Evelyn Tiffany-Castiglioni


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Summary

Well-respected leaders in the field of in vitro neurotoxicology take a fresh look at their own and other's work, critically and comparatively analyzing it across experimental systems and toxicants, and synthesizing essential principles for in vitro neurotoxicity testing.

In Vitro Neurotoxicology Summary

In Vitro Neurotoxicology: Principles and Challenges by Evelyn Tiffany-Castiglioni

Well-respected leaders in the field of in vitro neurotoxicology take a fresh look at their own and other's work, critically and comparatively analyzing it across experimental systems and toxicants, and synthesizing essential principles for in vitro neurotoxicity testing. Neurotoxicants of significance to human health are emphasized, especially those for which metabolism and dose-responses are well well studied both in vivo and in vitro: lead, mercury, organophosphorous insecticides, polychlorinated biphenyls and dioxin, ethanol, and endogenous proteins. The goal is to set out new concepts and research directions that will hasten significant improvement in the methods and systems for in vitro neurotoxicity testing.

In Vitro Neurotoxicology Reviews

This book covers a wide range of topics, starting with a nice overview of the field of neurotoxicology. Moving on to the meat of the material, the effects of toxins on neural development, function, and degeneration are examined, using well studied neurotoxicants as examples. A thorough list of articles as well as an annotated reading list are valuable additions, making the book an excellent reference. This is a valuable reference for anyone studying the advances in neurotoxicology. It is concise and easy to comprehend, without sacrificing quality in the process. It is written by leaders in the field, ensuring the information is relevant and up-to-date.-Doody's Health Sciences Book Review Journal

This is a useful book that updates new an improved in vitro methods to help further understanding neurotoxicology. The information presented is exciting, the methods proposed are often innovative, and readers will find a challenging glimpse into the future contributions their own research efforts can generate. Neurotoxicologists will find studying this volume rewarding and inspiring. - Vet Human Toxicol

...a helpful and up to date book... - BTS Newsletter

Table of Contents

In Vitro Neurotoxicology: Introduction to Concepts Evelyn Tiffany-Castiglioni Predictive Value of In Vitro Systems for Neurotoxicity Risk Assessment Marion Ehrich and David C. Dorman Exposure-Dose-Response Paradigm as It Relates to Toxicogenomics William H. Hanneman, Melvin E. Andersen, Marie E. Legare, Christine T. French, Tami S. McMullin, Carolyn Broccardo, and Ruth E. Billings In Vitro Studies of Neurotoxicant Effects on Cellular Homeostasis Gerald J. Audesirk and Ronald B. Tjalkens Role of Apoptosis in Neurotoxicology Lori D. White, Sid Hunter, Michael W. Miller, Marion Ehrich, and Stanley Barone, Jr. Impairment of Neurotransmitter Metabolism and Function by Neurotoxicants: Enzyme Pathways in Neurons and Astroglia Michael Aschner and Ursula Sonnewald Cell-Type-Specific Responses of the Nervous System to Lead Evelyn Tiffany-Castiglioni and Yongchang Qian Effects of Toxicants on Neural Differentiation Stanley Barone, Jr., Prasada R. S. Kodavanti, and William R. Mundy Impairment of Synaptic Function by Exposure to Lead Stephen M. Lasley and Mary E. Gilbert Aggregating Brain Cell Cultures for Neurotoxicological Studies Marie-Gabrielle Zurich, Florianne Monnet-Tschudi, Lucio G. Costa, Benoit Schilter, and Paul Honegger Use of Complimentary In Vitro and In Vivo Methods for Assessing Neuroendocrine Disruptors W. Les Dees, Jill K. Hiney, Robert K. Dearth, and Vinod K. Srivastava Establishing In Vitro Models to Study Endogenous Neurotoxicants Heather D. Durham Appendix: Annotated Reading List Evelyn Tiffany-Castiglioni, Lucio G. Costa, Marion Ehrich, William R. Mundy, Gerald J. Audesirk, Michael Aschner, Prasada R. S. Kodavanti, and Stephen M. Lasley Index

Additional information

NLS9781617373237
9781617373237
1617373230
In Vitro Neurotoxicology: Principles and Challenges by Evelyn Tiffany-Castiglioni
New
Paperback
Humana Press Inc.
2010-11-09
331
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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