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Vascular Responses to Pathogens Summary

Vascular Responses to Pathogens by Felicity N.E. Gavins (Associate Professor and Director of Small Animal Imaging Facility at LSU Health Sciences Center, Shreveport, LA, USA)

Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease.

About Felicity N.E. Gavins (Associate Professor and Director of Small Animal Imaging Facility at LSU Health Sciences Center, Shreveport, LA, USA)

Dr. Gavins is a pharmacologist whose research interest focuses on developing anti-inflammatory strategies that promote resolution of inflammation following ischemia reperfusion injury (I/RI) in cardiovascular and cerebrovascular diseases. She is specifically interested in the role of the microvasculature as a dynamic-interface between circulating blood- and immune-cells, lymphatics and tissue. Her group studies how circulating cells communicate, adhere and migrate across endothelial borders, along with investigating how circulating and resident cells can render systemic inflammatory responses and alter local inflammatory and thrombotic states. More recently Dr. Gavins has expanded her research to also cover microvascular dysfunction in the setting of organ transplantation, as evidenced by enhanced solute barrier function failure, neutrophil recruitment and endothelial damage. Dr. Stokes major area of research is the inflammatory impact of cytomegalovirus on the microvasculature. Her diverse research team is comprised of post-doctoral scientists and students, with an international reputation. Their research crosses the boundaries between Integrative Physiology and Pharmacology and uses multidisciplinary approaches to advance understanding of the vascular physiology and pathophysiology of inflammatory and related disorders, at the molecular, cellular, tissue and whole organism levels. In particular she and her team focus on the microcirculation, studying leukocyte trafficking and endothelial dysfunction in both the brain and the periphery.

Table of Contents

Chapter 1: Overview Chapter 2: Sepsis Chapter 3: Neutrophil Mediated Vascular Host Defense Chapter 4: Platelet-Bacteria Crosstalk Chapter 5: Mechanisms of bacterial interaction with cells of the blood-cerebrospinal fluid barrier Chapter 6: Vascular Responses to Chlamydia Pneumoniae Infection Chapter 7: Bartonella Species and Vascular Pathology Chapter 8: Periodontal Innate Immune Mechanisms Relevant to Atherosclerosis Chapter 9: H. Pylori Chapter 10: Vascular Responses to Pathogens: Rickettsia Chapter 11: Herpes Viruses Chapter 12: HIV/Antiretrovirals Chapter 13: Viral Myocarditis and Dilated Cardiomyopathy: Mechanisms of Cardiac Injury, Inflammation and Fibrosis Chapter 14: Viruses responsible for Hemorrhagic fevers Chapter 15: Trypanosoma cruzi and Chagas disease: Innate immunity, ROS, and Cardiovascular System Chapter 16: Endothelial cells as Targets of the intravascular parasitic disease Schistosomiasis Chapter 17: Vascular responses in Human Lymphatic Filariasis Chapter 18: The Treatment of Sepsis: From Failed Therapies to New Possibilities

Additional information

NPB9780128010785
9780128010785
0128010789
Vascular Responses to Pathogens by Felicity N.E. Gavins (Associate Professor and Director of Small Animal Imaging Facility at LSU Health Sciences Center, Shreveport, LA, USA)
New
Hardback
Elsevier Science Publishing Co Inc
2015-10-27
252
N/A
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