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Preface
Part I: Symptoms, Syndromes, and Diagnosis
1. Normal and Abnormal Mood
Abnormal Mood
Mania
Hypomania
The Syndrome of Depression
Mixed States
2. The Diagnosis of Bipolar Disorder
Psychiatric Diagnosis
Bipolar I
Bipolar II
Cyclothymic Disorder
Bipolar Spectrum Disorders
Rapid-Cycling Bipolar Disorder
Schizoaffective Disorder
3. Bipolar Disorder and the DSM-5
What Is the DSM?
Bipolar Categories in the DSM-5
4. The Mood Disease
Before "Bipolar"
Dr. Kraepelin and "Manic-Depressive Insanity"
Dr. Cade and Lithium
Part II: Treatment
5. The Plastic Brain
6. Mood-Stabilizing Medications
Lithium
Lamotrigine (Lamictal)
Valproate (Depakote, Depakene, Epival)
Carbamazepine (Tegretol, Equetro, Epitol)
Oxcarbazepine (Trileptal)
Other Mood Stabilizers
On the Horizon: Promising New Approaches
Antidepressant Medications
Tricyclic Antidepressants
Selective Serotonin Reuptake Inhibitors
New Antidepressants
Monoamine Oxidase Inhibitors
Treating Bipolar Depression
8. Antipsychotic Medications
Typical Antipsychotic Medications
Atypical Antipsychotic Medications
9. More Medications, Hormones, and Dietary Supplements
Medications for Anxiety and Sleep Disturbances
Thyroid Hormones
Herbal Preparations and Nutritional Supplements
Omega-3 Fatty Acids and Fish Oil
N-Acetyl Cysteine
St. John's Wort
10. Brain-Stimulation Treatments
Electroconvulsive Therapy
Transcranial Magnetic Stimulation
Vagal Nerve Stimulation
Emerging Technologies
11. Counseling and Psychotherapy
Brain and Mind
What Can Therapy Do?
Group Psychotherapy
Individual Therapy for Depression
New Psychotherapies for Bipolar Disorder
"Traditional" Individual Psychotherapy
Psychotherapy in Bipolar Disorder: Is It Really Necessary?
The Psychiatrist-Psychotherapist: An Extinct Species?
12. Treatment Approaches in Bipolar Disorder
Therapeutic Results as a Guide to Treatment
Some Principles of Treatment
Part III: Variations, Causes, and Connections
13. Bipolar Disorder in Children and Adolescents
Symptoms of Pediatric Bipolar Disorder
Bipolar Disorder and Attention-Deficit Hyperactivity Disorder
Treatment and Prognosis
14. Women with Bipolar Disorder: Special Considerations
Symptom Differences in Women
Postpartum Mood Disorders and Family Planning
Premenstrual Syndromes
15. Alcoholism and Drug Abuse
Bipolar Binges
Effect, Cause, or Association?
Use or Abuse?
A Deadly Combination
Treating Substance Abuse and Addiction
16. The Science of Cycles: Chronobiology
Circadian Rhythms
Seasonal Affective Disorder
The Sleep Cycle and Bipolar Disorder
17. The Genetics of Bipolar Disorder
Genes, Chromosomes, and DNA
Genetic Diseases
What We Know
The Search Continues
18. Bipolar Biology
How the Body Handles Stress
Bipolar Disorder and Hormonal Systems
Picturing Bipolar Disorder in the Brain
19. Bipolar Disorder and Creativity
Part IV: Getting Better and Staying Well
20. Living with Bipolar Disorder
Confront and Accept the Illness
Practice Mood Hygiene
Build Your Support System
Don't Be a "Bipolar Victim"
21. Planning for Emergencies
Know Whom to Call for Help
Insurance Issues
Safety Issues and Hospitalization
22. The Role of the Family
Recognizing Symptoms
Involuntary Treatment and Other Legal Issues
More on Safety
Getting Support
23. Looking Ahead
Resources
Suggested Reading
Support and Advocacy Organizations
Internet Resources
Notes
Index