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Advances in Immunology Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)

Advances in Immunology By Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)

Summary

Presents developments as well as comprehensive reviews in immunology. This book includes articles that address a range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities.

Advances in Immunology Summary

Advances in Immunology: Volume 110 by Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

Advances in Immunology Reviews

"The series which all immunologists need." --The Pharmaceutical Journal "Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions." --Science "Deserves a permanent place in biomedical libraries as an aid in research and in teaching." --Journal of Immunological Methods

About Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

Table of Contents

Modeling a Complex Disease: Multiple Sclerosis Florian C. Kurschus, Simone Wortge and Ari Waisman The IgH Locus 3 Regulatory Region: Pulling the Strings from Behind Eric Pinaud, Marie Marquet, Remi Fiancette, Sophie Peron, Christelle Vincent-Fabert, Yves Denizot and Michel Cogne Transcriptional and Epigenetic Regulation of CD4/CD8 Lineage Choice Ichiro Taniuchi and Wilfried Ellmeier Autoinflammation by Endogenous DNA Shigekazu Nagata and Kohki Kawane AID targeting in Antibody Diversity Rushad Pavri and Michel C. Nussenzweig

Additional information

NPB9780123876638
9780123876638
B007YXNETU
Advances in Immunology: Volume 110 by Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)
New
Hardback
Elsevier Science Publishing Co Inc
2011-08-31
184
N/A
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